Toxins superfamilies

1.08.01. Hok/gef family (1 family) PF01848 (Pfam)
1.08.02. Toxin Ibs (1 family) PF13956 (Pfam)
1.08.03. Lysis protein S family (1 family) PF04971 (Pfam)
1.08.04. Bacterial virulence factor haemolysin (1 family) PF10144 (Pfam)
1.08.05. Toxin TisB (1 family)
1.08.06. Small toxic protein ShoB (1 family)
1.08.07. Toxin Ldr (1 family) PF13940 (Pfam)
1.08.08. Macrophage perforin domain protein (1 family) PF01823 (Pfam)

Toxins (20 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.08.01.01. Regulatory protein MokC MOKC_ECOLI Escherichia coli Gram-neg. inner In 22-44 (11-46) 34.6 ± 1.7 1 ± 7 -20.9 -22.0
1.08.01.01. Protein HokA HOKA_ECOLI Escherichia coli Gram-neg. inner In 3-28 (2-28) 30.8 ± 3.4 30 ± 21 -16.7 -22.9
1.08.01.01. Protein HokB HOKB_ECOLI Escherichia coli Gram-neg. inner In 5-27 (5-31) 33.4 ± 2.0 2 ± 1 -18.5 -24.8
1.08.01.01. Protein HokC HOKC_ECOLI Escherichia coli Gram-neg. inner In 3-25 (2-27) 28.8 ± 1.8 1 ± 0 -19.6 -32.9
1.08.01.01. Protein HokD HOKD_ECOLI Escherichia coli Gram-neg. inner In 3-25 (2-27) 34.8 ± 2.5 1 ± 4 -20.2 -23.9
1.08.01.01. Protein HokE HOKE_ECOLI Escherichia coli Gram-neg. inner In 4-24 (4-24) 32.0 ± 3.5 6 ± 5 -15.8 -19.8
1.08.02.01. Small toxic protein IbsD IBSD_ECOLI Escherichia coli Gram-neg. inner Und 2-18 (2-19) 22.0 ± 2.2 2 ± 1 -12.8 -33.8
1.08.02.01. Small toxic protein IbsA IBSA_ECOLI Escherichia coli Gram-neg. inner Und 2-18 (2-19) 22.4 ± 1.8 2 ± 1 -8.0 -27.0
1.08.02.01. Small toxic protein IbsB IBSB_ECOLI Escherichia coli Gram-neg. inner Und 2-18 (2-18) 21.2 ± 1.0 5 ± 3 -5.0 -24.9
1.08.02.01. Small toxic protein IbsC IBSC_ECOLI Escherichia coli Gram-neg. inner Und 2-18 (2-19) 23.2 ± 1.6 0 ± 1 -11.3 -29.9
1.08.02.01. Small toxic protein IbsE IBSE_ECOLI Escherichia coli Gram-neg. inner Und 2-19 (2-19) 23.6 ± 1.2 0 ± 2 -8.2 -28.6
1.08.03.01. Lysis protein S homolog from lambdoid prophage DLP12 ESSD_ECOLI Escherichia coli Gram-neg. inner Out 36-58 (33-68) 34.6 ± 1.6 1 ± 1 -15.7 -19.0
1.08.03.01. Lysis protein S homolog from lambdoid prophage Qin ESSQ_ECOLI Escherichia coli Gram-neg. inner Out 36-58 (33-68) 34.8 ± 3.4 6 ± 5 -15.7 -19.2
1.08.04.01. Protein smp SMP_ECOLI Escherichia coli Gram-neg. inner Out 163-184 (161-189) 30.8 ± 3.3 2 ± 1 -12.8 -22.0
1.08.05.01. Small toxic protein TisB TISB_ECOLI Escherichia coli Gram-neg. inner Out 3-25 (3-28) 33.4 ± 0.7 30 ± 0 -12.4 -22.7
1.08.06.01. Small toxic protein ShoB SHOB_ECOLI Escherichia coli Gram-neg. inner Out 6-26 (3-26) 30.6 ± 3.4 13 ± 0 -9.0 -18.5
1.08.07.01. Small toxic polypeptide LdrA/LdrC LDRA_ECOLI Escherichia coli Gram-neg. inner Out 3-32 (3-34) 39.2 ± 1.4 0 ± 0 -11.0 -28.9
1.08.07.01. Small toxic polypeptide LdrB LDRB_ECOLI Escherichia coli Gram-neg. inner Out 6-32 (3-34) 30.8 ± 2.4 41 ± 2 -9.9 -20.1
1.08.07.01. Small toxic polypeptide LdrD LDRD_ECOLI Escherichia coli Gram-neg. inner Out 10-31 (8-34) 29.4 ± 4.0 14 ± 4 -7.9 -14.8
1.08.08.01. Macrophage-expressed gene 1 protein MPEG1_HUMAN Homo sapiens Plasma memb. Out 656-679 (656-680) 34.4 ± 2.2 8 ± 7 -14.8 -21.0