Ligases (EC 6.) and regulators superfamilies

1.14.01. Ubiquitin-protein ligase-related proteins (14 family)
1.14.02. Ubiquitin-conjugating enzyme (1 family) PF00179 (Pfam)
1.14.03. TRIM/RBCC family (1 family)
1.14.04. Osteopetrosis-associated transmembrane protein (1 family) PF09777 (Pfam)
1.14.05. F-box domain containing proteins (1 family) PF00646 (Pfam)
1.14.06. AMP-binding enzymes (3 families) PF00501 (Pfam)
1.14.07. ATP-dependent ligase (2 families)
1.14.08. Ankyrin repeat and SOCS box protein (1 family)

Ligases (EC 6.) and regulators (206 proteins)

Family Protein Name Protein ID Species Localization Topology TM Segment (helix) Hydrophobic Thickness (Å) Tilt Angle (°) ΔGfold (kcal/mol) ΔGtransf (kcal/mol)
1.14.01.01. Probable E3 ubiquitin-protein ligase RNF144A R144A_HUMAN Homo sapiens Plasma memb. In 250-278 (247-281) 34.8 ± 4.8 33 ± 2 -19.4 -28.9
1.14.01.01. E3 ubiquitin-protein ligase RNF144B R144B_HUMAN Homo sapiens Mito. outer memb. In 256-276 (255-280) 29.0 ± 3.8 1 ± 17 -11.7 -18.0
1.14.01.01. Probable E3 ubiquitin-protein ligase RNF217 RN217_HUMAN Homo sapiens Membrane In 497-529 (497-534) 42.8 ± 0.4 10 ± 1 -22.8 -54.2
1.14.01.01. Putative E3 ubiquitin-protein ligase ARI5 F4IAE4_ARATH Arabidopsis thaliana Membrane Und 70-92 (70-92) 33.4 ± 1.9 0 ± 0 -12.8 -25.9
1.14.01.01. RING/U-box superfamily protein F4IRP0_ARATH Arabidopsis thaliana Membrane Und 518-543 (515-545) 30.8 ± 6.0 40 ± 11 -9.0 -18.7
1.14.01.01. RING/U-box protein with C6HC-type zinc finger F4ITM1_ARATH Arabidopsis thaliana Membrane Und 373-395 (373-397) 30.0 ± 2.4 0 ± 0 -21.2 -47.3
1.14.01.01. RING/U-box protein with C6HC-type zinc finger F4ITM2_ARATH Arabidopsis thaliana Membrane Und 364-383 (364-383) 33.0 ± 2.9 13 ± 5 -11.2 -22.1
1.14.01.01. IBR domain containing protein Q1PEI1_ARATH Arabidopsis thaliana Membrane Und 363-385 (361-388) 33.2 ± 1.5 2 ± 3 -20.7 -27.8
1.14.01.01. RING/U-box protein with C6HC-type zinc finger F4J5L3_ARATH Arabidopsis thaliana Membrane Und 357-381 (357-381) 35.6 ± 3.8 17 ± 4 -24.9 -29.3
1.14.01.01. Putative uncharacterized protein F9K21.120 Q9M1F3_ARATH Arabidopsis thaliana Membrane Und 323-344 (323-347) 30.0 ± 2.0 2 ± 0 -16.8 -37.1
1.14.01.01. Uncharacterized protein Q54I29_DICDI Dictyostelium discoideum Membrane Und 335-356 (332-360) 30.8 ± 3.2 18 ± 10 -7.6 -14.9
1.14.01.01. Uncharacterized protein Q54ZG5_DICDI Dictyostelium discoideum Membrane Und 290-312 (289-314) 27.2 ± 2.0 0 ± 3 -15.5 -29.8
1.14.01.01. Uncharacterized protein Q54PV3_DICDI Dictyostelium discoideum Membrane Und 619-645 (619-651) 32.0 ± 5.6 43 ± 1 -15.6 -22.1
1.14.01.01. RING Zn finger-containing protein Q55AE0_DICDI Dictyostelium discoideum Membrane Und 825-853 (820-854) 31.6 ± 6.0 37 ± 7 -10.5 -20.9
1.14.01.01. Translation termination inhibitor protein ITT1 ITT1_YEAST Saccharomyces cerevisiae Membrane Und 121-141 (119-141) 30.8 ± 3.2 6 ± 12 -8.2 -19.7
1.14.01.02. E3 ubiquitin-protein ligase RNF130 GOLI_HUMAN Homo sapiens ER memb. Out 195-219 (194-227) 34.4 ± 2.2 3 ± 1 -21.7 -44.2
1.14.01.02. E3 ubiquitin-protein ligase RNF128 RN128_HUMAN Homo sapiens ER memb. Out 209-230 (205-234) 36.0 ± 1.6 0 ± 1 -19.4 -47.7
1.14.01.02. E3 ubiquitin-protein ligase RNF133 RN133_HUMAN Homo sapiens ER memb. Out 186-211 (178-211) 25.6 ± 1.8 3 ± 1 -17.3 -28.1
1.14.01.02. RING finger protein 148 RN148_HUMAN Homo sapiens Membrane Out 186-208 (181-209) 32.0 ± 2.1 4 ± 2 -16.9 -20.3
1.14.01.02. E3 ubiquitin-protein ligase RNF149 RN149_HUMAN Homo sapiens Vesicle memb. Out 200-224 (199-225) 34.8 ± 1.8 2 ± 1 -24.3 -44.6
1.14.01.02. RING finger protein 150 RN150_HUMAN Homo sapiens Membrane Out 207-232 (203-235) 38.0 ± 1.6 1 ± 0 -21.8 -53.4
1.14.01.02. E3 ubiquitin-protein ligase RNF167 RN167_HUMAN Homo sapiens Lysosome memb. Out 172-196 (172-201) 34.8 ± 3.8 9 ± 8 -16.2 -23.6
1.14.01.02. E3 ubiquitin-protein ligase RNF13 RNF13_HUMAN Homo sapiens ER memb. Out 179-207 (179-214) 30.8 ± 5.8 46 ± 0 -27.1 -31.1
1.14.01.02. Zinc/RING finger protein 4 ZNRF4_HUMAN Homo sapiens ER memb. Out 256-277 (250-281) 30.8 ± 2.8 1 ± 25 -16.3 -20.7
1.14.01.03. E3 ubiquitin-protein ligase RNF43 RNF43_HUMAN Homo sapiens Plasma memb. Out 197-220 (197-223) 34.4 ± 1.6 12 ± 6 -20.7 -25.7
1.14.01.03. E3 ubiquitin-protein ligase ZNRF3 ZNRF3_HUMAN Homo sapiens Plasma memb. Out 217-242 (213-245) 36.0 ± 1.6 0 ± 0 -24.9 -43.9
1.14.01.04. RING finger protein 122 RN122_HUMAN Homo sapiens ER memb. Und 39-61 (37-64) 30.8 ± 2.2 5 ± 4 -17.0 -34.1
1.14.01.04. RING finger protein 24 RNF24_HUMAN Homo sapiens Golgi memb. Und 24-47 (24-54) 30.8 ± 2.6 28 ± 25 -20.6 -22.6
1.14.01.05. RING finger protein 223 RN223_HUMAN Homo sapiens Membrane Und 197-219 (192-220) 32.2 ± 3.0 12 ± 8 -15.8 -23.1
1.14.01.05. E3 ubiquitin-protein ligase RNF152 RN152_HUMAN Homo sapiens Vacuole memb. Und 166-189 (164-195) 35.2 ± 1.8 0 ± 0 -19.2 -43.5
1.14.01.05. RING finger protein 183 RN183_HUMAN Homo sapiens Plasma memb. Und 158-185 (158-185) 35.2 ± 5.2 29 ± 1 -23.0 -28.0
1.14.01.05. RING finger protein 222 RN222_HUMAN Homo sapiens Membrane Und 193-216 (192-219) 34.0 ± 2.8 9 ± 9 -23.6 -27.2
1.14.01.05. RING finger protein 225 RN225_HUMAN Homo sapiens Plasma memb. Und 196-222 (194-223) 34.8 ± 2.0 26 ± 8 -19.2 -24.8
1.14.01.06. E3 ubiquitin-protein ligase RNF180 RN180_HUMAN Homo sapiens ER memb. In 569-590 (565-590) 29.6 ± 1.9 25 ± 1 -13.2 -19.1
1.14.01.07. E3 ubiquitin-protein ligase RMA1 RMA1_ARATH Arabidopsis thaliana ER memb. In 231-249 (226-249) 29.8 ± 2.4 5 ± 3 -9.4 -21.3
1.14.01.07. RING-H2 finger protein ATL14 ATL14_ARATH Arabidopsis thaliana Membrane Out 36-72 (36-72) 40.4 ± 4.2 42 ± 10 -26.8 -35.7
1.14.01.07. RING-H2 finger protein ATL75 ATL75_ARATH Arabidopsis thaliana Plasma memb. Out 57-80 (57-85) 34.0 ± 2.2 0 ± 5 -12.8 -19.6
1.14.01.07. E3 ubiquitin-protein ligase ATL76 ATL76_ARATH Arabidopsis thaliana Membrane Out 57-79 (57-84) 30.2 ± 2.3 20 ± 6 -12.6 -19.2
1.14.01.07. RING-H2 finger protein ATL77 ATL77_ARATH Arabidopsis thaliana Membrane Out 51-73 (50-81) 28.8 ± 1.4 2 ± 1 -12.4 -27.1
1.14.01.07. RING-H2 finger protein ATL78 ATL78_ARATH Arabidopsis thaliana ER memb. Out 52-73 (52-73) 31.0 ± 2.4 7 ± 5 -9.6 -17.7
1.14.01.07. RING-H2 finger protein ATL79 ATL79_ARATH Arabidopsis thaliana Plasma memb. Out 36-61 (33-62) 35.6 ± 1.2 0 ± 0 -20.3 -48.1
1.14.01.07. RING-H2 finger protein ATL7 ATL7_ARATH Arabidopsis thaliana Membrane Out 30-53 (22-57) 35.6 ± 4.0 8 ± 6 -24.1 -27.5
1.14.01.07. RING-H2 finger protein ATL80 ATL80_ARATH Arabidopsis thaliana Membrane Out 28-50 (28-61) 33.4 ± 2.0 1 ± 0 -22.3 -23.7
1.14.01.07. RING-H2 finger protein ATL81 ATL81_ARATH Arabidopsis thaliana Membrane Out 73-102 (73-104) 30.8 ± 3.2 53 ± 3 -18.5 -30.0
1.14.01.07. RING-H2 finger protein ATL8 ATL8_ARATH Arabidopsis thaliana Membrane Out 27-48 (26-60) 32.4 ± 5.2 1 ± 0 -21.8 -24.4
1.14.01.07. E3 ubiquitin-protein ligase ATL9 ATL9_ARATH Arabidopsis thaliana Membrane Out 50-72 (50-75) 32.2 ± 3.0 29 ± 0 -22.6 -32.1
1.14.01.07. RING-H2 finger protein ATL70 ATL70_ARATH Arabidopsis thaliana Plasma memb. Out 66-88 (58-90) 33.4 ± 1.9 1 ± 0 -16.4 -18.5
1.14.01.07. Putative RING-H2 finger protein ATL71 ATL71_ARATH Arabidopsis thaliana Membrane Out 25-47 (22-49) 32.2 ± 3.7 1 ± 1 -15.4 -18.9
1.14.01.07. RING-H2 finger protein ATL72 ATL72_ARATH Arabidopsis thaliana Membrane Out 27-48 (26-50) 29.2 ± 1.2 0 ± 2 -16.1 -37.5
1.14.01.07. RING-H2 finger protein ATL73 ATL73_ARATH Arabidopsis thaliana Membrane Out 40-62 (39-67) 32.4 ± 3.6 1 ± 8 -19.6 -18.6
1.14.01.07. RING-H2 finger protein ATL74 ATL74_ARATH Arabidopsis thaliana Membrane Out 30-55 (30-60) 30.8 ± 3.8 34 ± 4 -23.5 -25.1
1.14.01.07. Putative RING-H2 finger protein ATL69 ATL69_ARATH Arabidopsis thaliana Membrane Out 16-38 (15-42) 31.0 ± 2.5 10 ± 0 -20.7 -21.7
1.14.01.07. E3 ubiquitin-protein ligase ATL6 ATL6_ARATH Arabidopsis thaliana Plasma memb. Out 47-72 (47-74) 29.6 ± 1.2 0 ± 0 -25.1 -41.7
1.14.01.07. RING-H2 finger protein ATL64 ATL64_ARATH Arabidopsis thaliana Membrane Out 26-48 (26-50) 31.2 ± 3.2 1 ± 12 -19.9 -23.6
1.14.01.07. RING-H2 finger protein ATL65 ATL65_ARATH Arabidopsis thaliana Plasma memb. Out 40-61 (40-65) 32.2 ± 2.3 14 ± 0 -20.0 -27.9
1.14.01.07. RING-H2 finger protein ATL66 ATL66_ARATH Arabidopsis thaliana Membrane Out 32-53 (31-56) 33.4 ± 2.0 0 ± 1 -22.6 -30.4
1.14.01.07. RING-H2 finger protein ATL67 ATL67_ARATH Arabidopsis thaliana Membrane Out 32-60 (28-65) 28.0 ± 8.8 45 ± 2 -18.6 -21.7
1.14.01.07. RING-H2 finger protein ATL68 ATL68_ARATH Arabidopsis thaliana Membrane Out 30-49 (28-54) 29.8 ± 2.6 2 ± 1 -18.6 -18.6
1.14.01.07. Putative RING-H2 finger protein ATL62 ATL62_ARATH Arabidopsis thaliana Plasma memb. Out 11-30 (3-34) 29.8 ± 3.2 1 ± 11 -7.8 -18.2
1.14.01.07. RING-H2 finger protein ATL63 ATL63_ARATH Arabidopsis thaliana Endosome memb. Out 29-51 (24-53) 33.6 ± 1.4 2 ± 0 -30.6 -31.7
1.14.01.07. Putative RING-H2 finger protein ATL50 ATL50_ARATH Arabidopsis thaliana Membrane Out 31-60 (26-62) 38.0 ± 4.6 32 ± 0 -25.7 -31.0
1.14.01.07. RING-H2 finger protein ATL51 ATL51_ARATH Arabidopsis thaliana Membrane Out 56-79 (56-83) 34.0 ± 3.2 1 ± 0 -19.7 -26.5
1.14.01.07. RING-H2 finger protein ATL52 ATL52_ARATH Arabidopsis thaliana Membrane Out 53-77 (45-81) 34.4 ± 3.0 1 ± 2 -19.7 -26.1
1.14.01.07. RING-H2 finger protein ATL56 ATL56_ARATH Arabidopsis thaliana Membrane Out 28-57 (28-65) 30.8 ± 5.6 53 ± 1 -27.3 -37.1
1.14.01.07. RING-H2 finger protein ATL57 ATL57_ARATH Arabidopsis thaliana Mito. outer memb. Out 49-71 (48-71) 29.6 ± 2.0 2 ± 1 -24.6 -39.8
1.14.01.07. RING-H2 finger protein ATL58 ATL58_ARATH Arabidopsis thaliana Membrane Out 21-46 (17-51) 32.0 ± 4.8 27 ± 22 -23.4 -27.7
1.14.01.07. E3 ubiquitin-protein ligase ATL59 ATL59_ARATH Arabidopsis thaliana Membrane Out 18-43 (16-45) 36.4 ± 2.4 6 ± 4 -23.4 -31.4
1.14.01.07. RING-H2 finger protein ATL5 ATL5_ARATH Arabidopsis thaliana Plasma memb. Out 26-49 (26-50) 33.6 ± 2.0 22 ± 1 -22.8 -26.7
1.14.01.07. RING-H2 finger protein ATL60 ATL60_ARATH Arabidopsis thaliana Membrane Out 21-53 (18-55) 30.8 ± 1.4 52 ± 0 -20.3 -28.8
1.14.01.07. Putative RING-H2 finger protein ATL61 ATL61_ARATH Arabidopsis thaliana Membrane Out 5-37 (3-40) 30.0 ± 3.4 55 ± 0 -20.0 -29.9
1.14.01.07. Putative RING-H2 finger protein ATL53 ATL53_ARATH Arabidopsis thaliana Membrane Out 60-81 (60-85) 31.8 ± 2.5 28 ± 3 -21.8 -26.3
1.14.01.07. RING-H2 finger protein ATL54 ATL54_ARATH Arabidopsis thaliana Membrane Out 83-107 (82-110) 29.6 ± 2.8 40 ± 0 -20.8 -26.2
1.14.01.07. E3 ubiquitin-protein ligase RING1 ATL55_ARATH Arabidopsis thaliana Plasma memb. Out 41-69 (41-75) 34.4 ± 2.8 31 ± 3 -22.3 -30.6
1.14.01.07. RING-H2 finger protein ATL47 ATL47_ARATH Arabidopsis thaliana Membrane Out 51-76 (51-81) 36.8 ± 1.6 8 ± 3 -25.3 -54.8
1.14.01.07. Putative RING-H2 finger protein ATL49 ATL49_ARATH Arabidopsis thaliana Membrane Out 42-67 (41-69) 32.4 ± 4.8 30 ± 2 -20.2 -26.6
1.14.01.07. E3 ubiquitin-protein ligase ATL4 ATL4_ARATH Arabidopsis thaliana Plasma memb. Out 27-52 (26-54) 35.6 ± 3.2 12 ± 8 -22.6 -28.0
1.14.01.07. RING-H2 finger protein ATL43 ATL43_ARATH Arabidopsis thaliana Membrane Out 54-80 (54-85) 38.8 ± 5.0 0 ± 0 -26.2 -32.2
1.14.01.07. RING-H2 finger protein ATL44 ATL44_ARATH Arabidopsis thaliana Membrane Out 28-52 (25-57) 36.0 ± 2.4 0 ± 0 -18.4 -41.1
1.14.01.07. RING-H2 finger protein ATL45 ATL45_ARATH Arabidopsis thaliana Membrane Out 21-49 (21-55) 35.2 ± 3.8 3 ± 2 -18.6 -37.4
1.14.01.07. RING-H2 finger protein ATL46 ATL46_ARATH Arabidopsis thaliana Membrane Out 44-69 (43-72) 30.4 ± 5.2 38 ± 1 -23.9 -28.7
1.14.01.07. RING-H2 finger protein ATL1 ATL1_ARATH Arabidopsis thaliana ER memb. Out 41-65 (41-68) 37.6 ± 0.8 0 ± 1 -21.4 -40.6
1.14.01.07. RING-H2 finger protein ATL20 ATL20_ARATH Arabidopsis thaliana Membrane Out 171-193 (171-196) 32.4 ± 4.0 31 ± 16 -10.8 -15.3
1.14.01.07. RING-H2 finger protein ATL22 ATL22_ARATH Arabidopsis thaliana Membrane Out 242-265 (239-268) 35.2 ± 5.6 1 ± 1 -10.7 -19.6
1.14.01.07. E3 ubiquitin-protein ligase ATL23 ATL23_ARATH Arabidopsis thaliana Plasma memb. Out 27-53 (27-63) 35.2 ± 3.6 29 ± 0 -25.3 -32.8
1.14.01.07. RING-H2 finger protein ATL28 ATL28_ARATH Arabidopsis thaliana Membrane Out 21-49 (21-53) 41.2 ± 2.0 0 ± 0 -23.7 -48.4
1.14.01.07. RING-H2 finger protein ATL29 ATL29_ARATH Arabidopsis thaliana Membrane Out 22-43 (22-44) 29.8 ± 3.0 34 ± 3 -23.0 -33.2
1.14.01.07. RING-H2 finger protein ATL2 ATL2_ARATH Arabidopsis thaliana ER memb. Out 26-52 (24-61) 32.8 ± 2.0 39 ± 0 -27.7 -31.9
1.14.01.07. RING-H2 finger protein ATL30 ATL30_ARATH Arabidopsis thaliana Membrane Out 24-48 (24-54) 31.2 ± 4.8 40 ± 3 -25.3 -35.0
1.14.01.07. E3 ubiquitin-protein ligase ATL31 ATL31_ARATH Arabidopsis thaliana Membrane Out 41-65 (41-69) 33.2 ± 2.4 0 ± 2 -25.7 -41.7
1.14.01.07. RING-H2 finger protein ATL32 ATL32_ARATH Arabidopsis thaliana Membrane Out 46-67 (44-72) 28.8 ± 2.2 6 ± 4 -18.6 -34.6
1.14.01.07. RING-H2 finger protein ATL33 ATL33_ARATH Arabidopsis thaliana Membrane Out 59-83 (59-83) 35.6 ± 4.2 12 ± 4 -18.9 -30.0
1.14.01.07. RING-H2 finger protein ATL34 ATL34_ARATH Arabidopsis thaliana Membrane Out 44-67 (44-71) 34.8 ± 4.6 14 ± 12 -19.8 -26.3
1.14.01.07. Putative RING-H2 finger protein ATL35 ATL35_ARATH Arabidopsis thaliana Membrane Out 47-75 (47-82) 31.6 ± 4.4 42 ± 0 -21.2 -26.0
1.14.01.07. Putative RING-H2 finger protein ATL36 ATL36_ARATH Arabidopsis thaliana Membrane Out 48-72 (48-79) 32.8 ± 2.0 30 ± 14 -18.1 -21.6
1.14.01.07. Putative RING-H2 finger protein ATL37 ATL37_ARATH Arabidopsis thaliana Membrane Out 46-67 (45-69) 27.2 ± 1.6 1 ± 1 -18.7 -39.1
1.14.01.07. RING-H2 finger protein ATL38 ATL38_ARATH Arabidopsis thaliana Membrane Out 10-38 (10-40) 29.6 ± 3.6 45 ± 0 -24.0 -29.6
1.14.01.07. RING-H2 finger protein ATL39 ATL39_ARATH Arabidopsis thaliana Membrane Out 9-30 (8-32) 32.6 ± 2.4 5 ± 2 -16.6 -23.0
1.14.01.07. RING-H2 finger protein ATL3 ATL3_ARATH Arabidopsis thaliana Nucleus inner memb. Out 17-45 (17-46) 30.8 ± 4.8 40 ± 0 -29.2 -31.0
1.14.01.07. RING-H2 finger protein ATL40 ATL40_ARATH Arabidopsis thaliana Membrane Out 27-48 (22-58) 32.4 ± 4.2 8 ± 15 -21.3 -29.2
1.14.01.07. E3 ubiquitin-protein ligase ATL41 ATL41_ARATH Arabidopsis thaliana Plasma memb. Out 32-57 (29-62) 34.8 ± 1.6 23 ± 0 -20.4 -22.9
1.14.01.07. E3 ubiquitin-protein ligase ATL42 ATL42_ARATH Arabidopsis thaliana Membrane Out 37-59 (35-59) 33.6 ± 2.8 7 ± 5 -20.9 -27.3
1.14.01.07. RING-H2 finger protein ATL13 ATL13_ARATH Arabidopsis thaliana Membrane Out 50-75 (49-77) 31.2 ± 3.8 32 ± 4 -20.7 -26.2
1.14.01.07. E3 ubiquitin-protein ligase ATL15 ATL15_ARATH Arabidopsis thaliana Membrane Out 35-60 (28-62) 37.6 ± 3.2 1 ± 0 -20.5 -28.4
1.14.01.07. RING-H2 finger protein ATL16 ATL16_ARATH Arabidopsis thaliana Plasma memb. Out 33-58 (33-61) 34.4 ± 2.4 32 ± 27 -22.3 -28.8
1.14.01.07. RING-H2 finger protein ATL17 ATL17_ARATH Arabidopsis thaliana Membrane Out 2-22 (2-25) 29.8 ± 3.0 13 ± 5 -21.4 -23.6
1.14.01.07. RING-H2 finger protein ATL18 ATL18_ARATH Arabidopsis thaliana Membrane In 125-144 (121-144) 29.0 ± 2.7 0 ± 0 -12.8 -18.6
1.14.01.07. Putative RING-H2 finger protein ATL19 ATL19_ARATH Arabidopsis thaliana Membrane Out 7-43 (7-44) 30.8 ± 1.0 58 ± 0 -28.8 -35.9
1.14.01.07. RING-H2 finger protein ATL11 ATL11_ARATH Arabidopsis thaliana Golgi memb. Out 61-84 (61-89) 31.6 ± 2.0 0 ± 4 -24.0 -40.1
1.14.01.07. Putative RING-H2 finger protein ATL12 ATL12_ARATH Arabidopsis thaliana Membrane Out 40-63 (39-63) 31.6 ± 2.4 0 ± 3 -17.9 -50.0
1.14.01.07. Putative RING-H2 finger protein ATL21A AT21A_ARATH Arabidopsis thaliana Membrane Out 236-261 (236-266) 30.8 ± 7.0 43 ± 8 -14.3 -18.5
1.14.01.07. Putative RING-H2 finger protein ATL21B AT21B_ARATH Arabidopsis thaliana Membrane Out 232-256 (232-258) 35.6 ± 5.2 8 ± 7 -19.5 -23.5
1.14.01.07. Putative RING-H2 finger protein ATL21C AT21C_ARATH Arabidopsis thaliana Membrane Out 241-266 (240-269) 30.8 ± 3.6 30 ± 3 -14.7 -22.3
1.14.01.07. RING-H2 finger protein ATL10 ATL10_ARATH Arabidopsis thaliana Membrane Out 57-79 (56-84) 32.0 ± 2.4 1 ± 0 -14.2 -19.0
1.14.01.07. Uncharacterized protein DDB_G0292642 Y5521_DICDI Dictyostelium discoideum Membrane In 861-886 (855-890) 30.0 ± 4.8 36 ± 0 -17.6 -21.7
1.14.01.08. E3 ubiquitin-protein ligase RMA3 RMA3_ARATH Arabidopsis thaliana ER memb. In 225-243 (218-243) 26.8 ± 3.4 6 ± 1 -7.7 -27.8
1.14.01.08. E3 ubiquitin-protein ligase RMA2 RMA2_ARATH Arabidopsis thaliana ER memb. In 175-193 (171-193) 29.8 ± 2.8 4 ± 3 -10.5 -21.6
1.14.01.09. E3 ubiquitin-protein ligase ORTHRUS-LIKE 1 ORTHL_ARATH Arabidopsis thaliana Nucleus memb. Und 440-462 (434-464) 32.8 ± 2.9 1 ± 8 -21.4 -23.6
1.14.01.10. Probable E3 ubiquitin-protein ligase HECTD4 HECD4_HUMAN Homo sapiens Vesicle memb. Und 282-301 (280-301) 29.6 ± 3.4 2 ± 8 -5.7 -19.4
1.14.01.11. Receptor homology region, transmembrane domain- and RING domain-containing protein 1 RMR1_ARATH Arabidopsis thaliana Vacuole memb. Out 167-190 (165-190) 34.8 ± 2.2 0 ± 0 -24.5 -49.2
1.14.01.11. Receptor homology region, transmembrane domain- and RING domain-containing protein 2 RMR2_ARATH Arabidopsis thaliana Vacuole memb. Out 162-185 (158-193) 36.0 ± 2.2 3 ± 0 -20.0 -50.5
1.14.01.11. Receptor homology region, transmembrane domain- and RING domain-containing protein 3 RMR3_ARATH Arabidopsis thaliana Vacuole memb. Out 165-190 (161-192) 38.0 ± 4.6 1 ± 0 -24.2 -26.7
1.14.01.11. Receptor homology region, transmembrane domain- and RING domain-containing protein 4 RMR4_ARATH Arabidopsis thaliana Vacuole memb. Out 164-187 (160-195) 32.0 ± 2.2 3 ± 1 -20.0 -44.9
1.14.01.11. Receptor homology region, transmembrane domain- and RING domain-containing protein 5 RMR5_ARATH Arabidopsis thaliana Vacuole memb. Out 162-184 (161-188) 32.4 ± 1.0 1 ± 0 -17.8 -39.2
1.14.01.11. Receptor homology region, transmembrane domain- and RING domain-containing protein 6 RMR6_ARATH Arabidopsis thaliana Vacuole memb. Out 162-184 (161-188) 31.2 ± 2.4 0 ± 0 -19.0 -29.0
1.14.01.12. Putative E3 ubiquitin-protein ligase XBAT31 F4IJM9_ARATH Arabidopsis thaliana Membrane Und 32-52 (28-53) 29.4 ± 2.3 15 ± 6 -16.5 -21.3
1.14.01.13. Mitochondrial ubiquitin ligase activator of NFKB 1 MUL1_HUMAN Homo sapiens Mito. outer memb. In 239-259 (234-261) 32.2 ± 2.6 4 ± 0 -16.7 -25.4
1.14.01.13. At1g59560 Q94HV7_ARATH Arabidopsis thaliana Membrane Und 222-239 (217-239) 28.4 ± 1.7 1 ± 0 -7.7 -14.4
1.14.01.13. RING-type ubiquitin E3 ligase F4I570_ARATH Arabidopsis thaliana Membrane Und 223-248 (219-253) 30.4 ± 2.2 32 ± 3 -12.0 -19.1
1.14.01.14. Cell growth regulator with RING finger domain protein 1 CGRF1_HUMAN Homo sapiens Membrane Und 12-38 (12-38) 34.0 ± 2.8 0 ± 2 -13.9 -45.6
1.14.01.14. At4g33940 Q501G9_ARATH Arabidopsis thaliana Membrane Und 215-236 (214-239) 31.4 ± 3.6 12 ± 2 -12.6 -21.5
1.14.01.14. At1g19310/F18O14_14 Q9LN67_ARATH Arabidopsis thaliana Membrane Und 206-226 (203-226) 29.4 ± 1.9 9 ± 5 -17.8 -24.0
1.14.01.14. F21J9.10 Q9FYL9_ARATH Arabidopsis thaliana Membrane Und 41-63 (37-63) 26.0 ± 2.0 0 ± 3 -7.4 -23.8
1.14.01.14. Putative RING zinc finger protein O64824_ARATH Arabidopsis thaliana Membrane Und 208-227 (205-227) 30.0 ± 3.8 9 ± 5 -9.6 -32.0
1.14.01.14. Protein ABERRANT POLLEN DEVELOPMENT 1 F4IS11_ARATH Arabidopsis thaliana Membrane Und 209-231 (207-233) 31.6 ± 2.2 1 ± 0 -11.7 -32.0
1.14.01.14. RING-finger domain-containing protein F4JQ58_ARATH Arabidopsis thaliana Membrane Und 20-45 (20-48) 30.4 ± 3.4 36 ± 6 -14.4 -19.3
1.14.01.14. NEP1-interacting protein-like 1 NIPL1_ARATH Arabidopsis thaliana Membrane Und 22-48 (19-51) 42.8 ± 1.0 0 ± 0 -20.4 -60.1
1.14.01.14. E3 ubiquitin-protein ligase RHA2A RHA2A_ARATH Arabidopsis thaliana Membrane Und 14-32 (14-37) 29.0 ± 1.9 8 ± 9 -8.4 -15.8
1.14.01.14. Probable E3 ubiquitin-protein ligase RHA2B RHA2B_ARATH Arabidopsis thaliana Membrane Und 9-30 (9-33) 29.0 ± 3.1 19 ± 9 -7.2 -20.1
1.14.01.14. RING-H2 zinc finger protein RHA4a RHA4A_ARATH Arabidopsis thaliana Membrane Und 24-47 (14-51) 34.0 ± 4.4 4 ± 10 -27.3 -27.3
1.14.01.14. F6A14.12 protein Q9M9U8_ARATH Arabidopsis thaliana Membrane Und 14-34 (14-37) 30.6 ± 2.7 18 ± 2 -12.7 -18.4
1.14.01.14. Putative uncharacterized protein At3g43430 Q9M176_ARATH Arabidopsis thaliana Membrane Und 9-34 (6-39) 32.4 ± 4.8 30 ± 0 -11.5 -18.4
1.14.01.14. At5g01980 Q9LZN3_ARATH Arabidopsis thaliana Membrane Und 445-468 (441-469) 34.8 ± 3.6 4 ± 4 -12.7 -22.3
1.14.01.14. At1g51930 Q6AWX4_ARATH Arabidopsis thaliana Membrane Und 4-24 (4-25) 30.8 ± 3.4 24 ± 23 -10.1 -20.7
1.14.01.14. HRD1-like protein Q27GM7_ARATH Arabidopsis thaliana Membrane Und 42-62 (38-62) 29.6 ± 3.4 6 ± 14 -9.7 -19.1
1.14.01.14. At2g28920 Q9ZV22_ARATH Arabidopsis thaliana Membrane Und 26-51 (23-51) 34.0 ± 3.4 32 ± 0 -21.2 -27.9
1.14.01.14. At2g34000 O22953_ARATH Arabidopsis thaliana Membrane Und 11-36 (10-39) 30.0 ± 1.4 0 ± 0 -23.8 -45.8
1.14.01.14. RING/U-box domain-containing protein B3H6J7_ARATH Arabidopsis thaliana Membrane Und 12-33 (11-34) 32.0 ± 2.4 13 ± 1 -10.0 -21.7
1.14.01.14. AT4g17240/dl4655c Q940N3_ARATH Arabidopsis thaliana Membrane Und 33-56 (32-59) 35.6 ± 2.2 0 ± 1 -22.1 -43.8
1.14.01.14. C3H2C3-type RING E3 Ub ligase F4JNK0_ARATH Arabidopsis thaliana Membrane Und 29-51 (29-56) 32.6 ± 3.6 2 ± 9 -14.0 -19.0
1.14.01.14. AT5g20880/F22D1_50 Q93ZD8_ARATH Arabidopsis thaliana Membrane Und 9-34 (6-40) 30.4 ± 2.2 35 ± 3 -13.0 -21.9
1.14.01.14. RING/U-box domain-containing protein-like protein F4K2W6_ARATH Arabidopsis thaliana Membrane Und 218-250 (218-255) 31.2 ± 1.8 53 ± 0 -14.9 -28.5
1.14.01.14. RING/U-box domain-containing protein Q9FN58_ARATH Arabidopsis thaliana Membrane Und 11-29 (10-32) 27.4 ± 2.3 6 ± 1 -15.4 -20.8
1.14.01.14. RING/U-box domain-containing protein Q9FN56_ARATH Arabidopsis thaliana Membrane Und 12-41 (12-43) 30.8 ± 0.0 50 ± 0 -23.8 -34.5
1.14.01.14. Emb Q9FN57_ARATH Arabidopsis thaliana Membrane Und 13-34 (10-34) 30.8 ± 2.2 19 ± 3 -15.7 -19.4
1.14.01.14. Expressed protein Q944Q6_ARATH Arabidopsis thaliana Membrane Und 303-328 (303-329) 36.0 ± 4.0 8 ± 2 -21.0 -23.9
1.14.01.14. RING/U-box domain-containing protein Q9FI95_ARATH Arabidopsis thaliana Membrane Und 23-43 (23-45) 31.4 ± 2.8 11 ± 4 -14.7 -21.0
1.14.01.14. RING/FYVE/PHD zinc finger-containing protein F4K7X6_ARATH Arabidopsis thaliana Membrane Und 180-201 (169-202) 29.0 ± 3.9 15 ± 8 -14.0 -21.1
1.14.01.14. At5g59000 Q2HIG9_ARATH Arabidopsis thaliana Membrane Und 206-230 (206-230) 30.8 ± 3.6 34 ± 4 -19.1 -23.8
1.14.01.14. At2g37950 Q5XEN4_ARATH Arabidopsis thaliana Membrane Und 181-202 (177-205) 31.6 ± 1.8 1 ± 0 -16.1 -37.3
1.14.01.14. Putative uncharacterized protein At2g34200/F13P17.4 Q84RF4_ARATH Arabidopsis thaliana Membrane Und 192-213 (183-216) 32.2 ± 3.3 5 ± 2 -19.6 -24.5
1.14.01.14. At5g05830 Q9FFJ5_ARATH Arabidopsis thaliana Membrane Und 178-199 (175-201) 31.6 ± 2.6 5 ± 3 -16.9 -37.3
1.14.01.14. Uncharacterized protein Q54ND8_DICDI Dictyostelium discoideum Membrane Und 262-280 (257-280) 31.4 ± 3.1 22 ± 18 -16.6 -24.9
1.14.01.14. RING/leucine zipper protein Q94491_DICDI Dictyostelium discoideum Membrane Und 36-54 (36-55) 26.8 ± 2.1 21 ± 6 -7.7 -16.0
1.14.01.14. Uncharacterized protein Q55EJ5_DICDI Dictyostelium discoideum Membrane Und 274-294 (270-294) 27.6 ± 3.1 25 ± 9 -9.4 -18.0
1.14.01.14. Uncharacterized protein Q54XT2_DICDI Dictyostelium discoideum Membrane Und 203-228 (203-231) 28.4 ± 2.6 46 ± 0 -10.3 -23.4
1.14.01.14. Uncharacterized protein Q556W9_DICDI Dictyostelium discoideum Membrane Und 144-168 (143-168) 30.8 ± 2.4 21 ± 4 -11.3 -17.0
1.14.02.01. Ubiquitin-conjugating enzyme E2 J1 UB2J1_HUMAN Homo sapiens ER memb. In 285-306 (283-309) 30.6 ± 2.9 1 ± 11 -16.0 -23.0
1.14.02.01. Ubiquitin-conjugating enzyme E2 J2 UB2J2_HUMAN Homo sapiens ER memb. In 232-256 (231-257) 30.0 ± 2.8 31 ± 26 -14.9 -19.5
1.14.02.01. Ubiquitin-conjugating enzyme E2 32 UBC32_ARATH Arabidopsis thaliana ER memb. In 274-295 (270-298) 32.2 ± 3.0 11 ± 11 -16.9 -24.5
1.14.02.01. Probable ubiquitin-conjugating enzyme E2 33 UBC33_ARATH Arabidopsis thaliana ER memb. In 220-241 (219-242) 31.4 ± 2.9 1 ± 1 -12.7 -21.5
1.14.02.01. Ubiquitin-conjugating enzyme E2 34 UBC34_ARATH Arabidopsis thaliana ER memb. In 214-235 (214-236) 31.2 ± 1.0 11 ± 0 -13.6 -23.1
1.14.02.01. Ubiquitin-conjugating enzyme E2 J2 UB2J2_DICDI Dictyostelium discoideum ER memb. In 221-241 (221-241) 30.6 ± 2.8 11 ± 2 -21.6 -24.7
1.14.02.01. Uncharacterized protein Q54U33_DICDI Dictyostelium discoideum Membrane Und 378-400 (375-400) 28.4 ± 2.0 0 ± 0 -12.5 -34.8
1.14.02.01. Ubiquitin-conjugating enzyme E2 6 UBC6_YEAST Saccharomyces cerevisiae ER memb. In 232-250 (229-250) 27.4 ± 2.7 1 ± 0 -16.4 -18.3
1.14.03.01. E3 ubiquitin-protein ligase TRIM13 TRI13_HUMAN Homo sapiens ER memb. In 314-336 (311-336) 33.6 ± 2.2 2 ± 2 -20.9 -28.8
1.14.03.01. Tripartite motif-containing protein 59 TRI59_HUMAN Homo sapiens ER memb. In 326-349 (321-351) 34.8 ± 2.8 6 ± 1 -20.4 -25.8
1.14.04.01. Osteopetrosis-associated transmembrane protein 1 OSTM1_HUMAN Homo sapiens Lysosome memb. Out 283-305 (282-312) 33.8 ± 1.9 4 ± 2 -16.8 -26.4
1.14.05.01. Putative F-box/FBD/LRR-repeat protein At3g23955 FDL17_ARATH Arabidopsis thaliana Membrane Und 18-40 (5-42) 29.6 ± 1.9 30 ± 22 -9.0 -15.4
1.14.05.01. F-box and associated interaction domain-containing protein F4HUN6_ARATH Arabidopsis thaliana Membrane Und 87-112 (83-115) 31.6 ± 5.8 33 ± 2 -5.9 -15.5
1.14.05.01. Putative F-box/kelch-repeat protein At1g20940 FBK7_ARATH Arabidopsis thaliana Membrane Und 106-124 (102-126) 26.8 ± 3.0 11 ± 6 -4.8 -30.7
1.14.05.01. F-box/kelch-repeat protein F4IR26_ARATH Arabidopsis thaliana Membrane Und 362-382 (362-384) 31.4 ± 2.8 8 ± 1 -10.6 -18.8
1.14.05.01. F-box/LRR-repeat protein At2g43260 FBL40_ARATH Arabidopsis thaliana Membrane Und 395-417 (391-418) 32.8 ± 2.0 7 ± 4 -8.4 -21.3
1.14.05.01. F-box protein At2g41170 FB132_ARATH Arabidopsis thaliana Membrane Und 6-27 (2-29) 31.2 ± 2.6 13 ± 4 -14.4 -19.5
1.14.05.01. F-box only protein 12 FBX12_ARATH Arabidopsis thaliana Membrane Und 380-400 (379-400) 29.8 ± 2.2 8 ± 5 -17.0 -20.7
1.14.05.01. F-box protein At3g44326 FB346_ARATH Arabidopsis thaliana Membrane Und 328-350 (327-351) 29.8 ± 2.7 29 ± 6 -20.3 -24.4
1.14.05.01. Putative F-box protein At1g67450 FB78_ARATH Arabidopsis thaliana Membrane Und 373-394 (364-397) 29.4 ± 4.0 36 ± 0 -17.6 -22.7
1.14.05.01. Putative F-box protein At1g77880 FB90_ARATH Arabidopsis thaliana Membrane Und 110-129 (105-129) 29.8 ± 2.3 4 ± 3 -5.5 -13.9
1.14.05.01. F-box protein At2g27310 FB119_ARATH Arabidopsis thaliana Membrane Und 315-336 (305-336) 30.4 ± 2.6 4 ± 2 -14.1 -22.4
1.14.05.01. F-box protein At5g10340 FB255_ARATH Arabidopsis thaliana Membrane Und 375-397 (362-399) 32.4 ± 7.0 1 ± 13 -15.6 -21.8
1.14.05.01. Putative F-box/LRR-repeat protein At3g49150 FBL54_ARATH Arabidopsis thaliana Membrane Und 587-606 (585-606) 29.0 ± 1.1 2 ± 0 -4.1 -13.6
1.14.05.01. F-box protein At3g57580 FB329_ARATH Arabidopsis thaliana Membrane Und 202-226 (201-228) 30.8 ± 3.2 29 ± 0 -4.1 -23.2
1.14.05.01. Putative F-box protein At4g17780 FB236_ARATH Arabidopsis thaliana Membrane Und 376-397 (376-397) 30.2 ± 2.3 11 ± 0 -6.3 -14.4
1.14.05.01. Putative F-box/kelch-repeat protein At5g28180 FK115_ARATH Arabidopsis thaliana Membrane Und 2-28 (2-32) 31.6 ± 3.4 52 ± 10 -28.7 -33.9
1.14.05.01. Probable F-box protein At1g60180 FB322_ARATH Arabidopsis thaliana Membrane Und 291-312 (291-317) 32.4 ± 2.5 31 ± 1 -19.4 -29.4
1.14.05.01. Uncharacterized protein Q54NN6_DICDI Dictyostelium discoideum Membrane Und 17-37 (17-38) 29.0 ± 4.0 22 ± 18 -12.4 -18.8
1.14.06.01. Long-chain-fatty-acid--CoA ligase 1 ACSL1_HUMAN Homo sapiens Mito. outer memb. Out 25-46 (24-47) 32.0 ± 2.6 12 ± 10 -11.0 -20.4
1.14.06.01. Long-chain-fatty-acid--CoA ligase 3 ACSL3_HUMAN Homo sapiens ER memb. Out 20-45 (20-48) 36.0 ± 2.2 25 ± 1 -11.9 -22.4
1.14.06.01. Long-chain-fatty-acid--CoA ligase 4 ACSL4_HUMAN Homo sapiens Golgi memb. Out 7-36 (7-38) 30.8 ± 0.8 52 ± 0 -17.1 -25.3
1.14.06.01. Long-chain-fatty-acid--CoA ligase 5 ACSL5_HUMAN Homo sapiens Mito. outer memb. Out 2-32 (2-34) 29.8 ± 1.6 60 ± 0 -13.5 -28.4
1.14.06.01. Long-chain-fatty-acid--CoA ligase 6 ACSL6_HUMAN Homo sapiens ER memb. Out 27-46 (25-46) 29.6 ± 3.5 3 ± 2 -14.5 -17.8
1.14.06.01. Long chain acyl-CoA synthetase 8 LACS8_ARATH Arabidopsis thaliana Membrane Und 20-44 (20-50) 30.4 ± 2.4 29 ± 0 -10.3 -17.2
1.14.06.02. Long-chain fatty acid transport protein 1 S27A1_HUMAN Homo sapiens Plasma memb. Out 8-33 (8-39) 30.8 ± 3.4 3 ± 1 -9.2 -25.5
1.14.06.03. Long-chain fatty acid transport protein 6 S27A6_HUMAN Homo sapiens Plasma memb. Und 27-47 (26-50) 29.0 ± 3.2 13 ± 1 -4.0 -21.0
1.14.07.01. Tyramine--L-glutamate ligase MFND_METJA Methanococcus jannaschii Archaebacterial memb. Und 4-25 (2-27) 30.8 ± 2.4 8 ± 13 -10.3 -19.6
1.14.07.02. Uncharacterized protein MJ0776 Y776_METJA Methanococcus jannaschii Archaebacterial memb. Und 3-24 (3-29) 26.4 ± 3.4 4 ± 2 -2.6 -21.5
1.14.08.01. Ankyrin repeat and SOCS box protein 11 ASB11_HUMAN Homo sapiens Membrane Und 13-38 (13-45) 28.4 ± 1.4 48 ± 0 -19.6 -31.9