WAKLN_ARATH » Wall-associated receptor kinase-like 18

WAKLN_ARATH » Wall-associated receptor kinase-like 18
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
WAKLN_ARATH » Wall-associated receptor kinase-like 18 »
Hydrophobic Thickness 32.0 ± 1.6 Å
Tilt Angle 0 ± 0°
ΔGtransfer -33.6 kcal/mol
ΔGfold -11.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 378-403 (374-406)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BETL2, Complex: WAKLN:BETL2

UBC34, Complex: WAKLN:UBC34

WAK3, Complex: WAKLN:WAK3

Domains

AA: 26-151, Wall-associated receptor kinase galacturonan-binding

AA: 207-316, Wall-associated kinase

AA: 453-725, PDBID: 3OMV, Subunit A, Seq Identity:44%, Protein tyrosine kinase

UniProt annotation for WAKLN_ARATH » Wall-associated receptor kinase-like 18
FUNCTION: Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

DOMAIN: The EGF-like region is specific to this family of proteins and seems to consist of the C-terminal of an EGF-like domain fused to the N-terminal of another one.

UniProt features for WAKLN_ARATH » Wall-associated receptor kinase-like 18
SIGNAL 1 28 Potential.
CHAIN 29 793 Wall-associated receptor kinase-like 18.
DOMAIN 453 728 Protein kinase.
REGION 312 371 Atypical EGF-like.
ACT_SITE 579 579 Proton acceptor (By similarity).
DISULFID 314 327 By similarity.
DISULFID 349 362 By similarity.
DISULFID 356 371 By similarity.
Amino Acid Sequence for WAKLN_ARATH » Wall-associated receptor kinase-like 18
MSNESTNCSF FLNLFMLLLL LIFYSADACQ RECGGISIPY PFGIGKDCCL EKYYEIECRN TTSRKLVPLL SFINKEVVSI SLPSADSHFA YEVSDQERHE SFGLVRVKFP ITSAGCFNDG KESGGGSKMN FTGSPFFIDR SNSLIAAGCN SKVSLMYIKP KMVGCELSCN TSKDSYSNSI PFVEAGCSSN VLPYSQDQGC PEEIAEETGC NGIGCCQASL PNEPQQVIGI RTENNDGNST TKVECTVSAF LTDEIYALPK ATKTEHLLAK RYATVSLGWV IQTSNRSFLD SLALACKDRE DYRNTTNLER KCTCGRITIS ETSYANCGCT YGYTGNPYVL NGCKDIDECK VKFEYCGKTE TCVNFEGGYR CVRDKTKAIM IGAGTGFGVL VLVGGLWWLR KFLIKRRITK RKKKFFKRNG GLLLLQELNT REGYVEKTRV FNSRELEKAT ENFSENRVLG HGGQGTVYKG MLVDGRTVAV KKSKVIDEDK LQEFINEVVI LSQINHRHVV KLLGCCLETE VPMLVYEFII NGNLFKHIHE EESDDYTMLW GMRLRIAVDI AGALSYLHSS ASSPIYHRDI KSTNILLDEK YRAKVADFGT SRSVTIDQTH WTTVISGTVG YVDPEYYQSS QYTEKSDVYS FGVILAELIT GDKPVIMVQN TQEIVALAEH FRVAMKEKRL TDIIDARIRN DCKPEQVMAV AKVAMKCLSS KGKKRPNMRE VFTELERICT SPEDSQVHNR IDEEEEEEEE EEEVVTTINR GDSWSISVTA PALSIVASSP SSDVEPLFPR LTW