WAKLM_ARATH » Wall-associated receptor kinase-like 17

WAKLM_ARATH » Wall-associated receptor kinase-like 17
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
WAKLM_ARATH » Wall-associated receptor kinase-like 17 »
Hydrophobic Thickness 33.6 ± 1.6 Å
Tilt Angle 0 ± 2°
ΔGtransfer -35.8 kcal/mol
ΔGfold -12.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 366-391 (365-400)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 31-143, Wall-associated receptor kinase galacturonan-binding

AA: 197-305, Wall-associated kinase

AA: 336-367, PDBID: 2KL7, Subunit A, Seq Identity:55%, Calcium-binding EGF domain

AA: 444-716, PDBID: 3TL8, Subunit A, Seq Identity:47%, Protein kinase domain

UniProt annotation for WAKLM_ARATH » Wall-associated receptor kinase-like 17
FUNCTION: Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

DOMAIN: The EGF-like region is specific to this family of proteins and seems to consist of the C-terminal of an EGF-like domain fused to the N-terminal of another one.

UniProt features for WAKLM_ARATH » Wall-associated receptor kinase-like 17
SIGNAL 1 30 Potential.
CHAIN 31 786 Wall-associated receptor kinase-like 17.
DOMAIN 444 719 Protein kinase.
REGION 301 362 Atypical EGF-like.
ACT_SITE 570 570 Proton acceptor (By similarity).
DISULFID 303 318 By similarity.
DISULFID 340 353 By similarity.
DISULFID 347 362 By similarity.
Amino Acid Sequence for WAKLM_ARATH » Wall-associated receptor kinase-like 17
MSYKNTNNSH LILFKLLLLL ILYSADLTAS SSCRSECGGC KCGGIAIPYP FGIGKGCYLE KSYEIECLNT SGKLVPFLSV ISKEVVSIHL PGRQSFGSVR VRSPITSAGC SSDGKDSAPV MNLTDSPFFV SDINNLVGVG CSSKVSLEHI KQNMVGCELN CSTTNASDSN SIPFFDKTGC SFSYTFAQVC TGNKPEDMGC DGRGCCQASL PREPQQVIGI RIESNDGKST TSGDCRVAFL TDEFFSLSKL TKPEQLHAKR YATLSLGWIM QTRNTSFVNS LACKIRKDTD TAYSNDQSIK CICDYTMSII SDIRYANCEC NLGYKGNPYD SDGCRDIDEC KENPKYCKET DTCVNFEGGY RCVGDKTKAI MIGAGTGFGV LVLVGGVWWL RKFLVKRRMA KRKKKFFKRN GGLLLQQELN TRQGVVEKAR IFTSKELEKA TENFSENRVL GHGGQGTVYK GMLVDGRTVA VKKSKVIDED KLQEFINEVV ILSQINHRHV VKLLGCCLET EVPILVYEFI INGNLFKHIH EEEADDYTMI WGMRLRIAVD IAGALSYLHS AASSPIYHRD IKSTNILLDE KYRAKVADFG TSRSVTIDQT HWTTVISGTV GYVDPEYYRS SQYTEKSDVY SFGVILAELI TGDKPVIMVQ NTQEIIALAE HFRVAMKERR LSDIMDARIR DDSKPEQVMA VANLAMKCLS SRGRNRPNMR EVFTELERIC TSPEDSQVQN RIDEEEEEDG VEEEEEVVTI VHRGDSWSIG VTAPASSIVA SPPSSDVEPL NPLLTW