WAKLF_ARATH » Wall-associated receptor kinase-like 6

WAKLF_ARATH » Wall-associated receptor kinase-like 6
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
WAKLF_ARATH » Wall-associated receptor kinase-like 6 »
Hydrophobic Thickness 37.2 ± 1.8 Å
Tilt Angle 1 ± 1°
ΔGtransfer -46.6 kcal/mol
ΔGfold -18.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 357-382 (352-385)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 39-160, Wall-associated receptor kinase galacturonan-binding

AA: 189-293, Wall-associated kinase

AA: 432-641, PDBID: 3TL8, Subunit A, Seq Identity:46%, Protein kinase domain

UniProt annotation for WAKLF_ARATH » Wall-associated receptor kinase-like 6
FUNCTION: Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Slightly expressed in the whole plant.

INDUCTION: Induced by INA.

DOMAIN: The EGF-like region is specific to this family of proteins and seems to consist of the C-terminal of an EGF-like domain fused to the N-terminal of another one.

UniProt features for WAKLF_ARATH » Wall-associated receptor kinase-like 6
SIGNAL 1 28 Potential.
CHAIN 29 642 Wall-associated receptor kinase-like 6.
DOMAIN 432 642 Protein kinase.
REGION 289 346 Atypical EGF-like.
ACT_SITE 559 559 Proton acceptor (By similarity).
DISULFID 291 304 By similarity.
DISULFID 326 337 By similarity.
DISULFID 332 346 By similarity.
Amino Acid Sequence for WAKLF_ARATH » Wall-associated receptor kinase-like 6
MKKTKTYQVF CIAALSVLTL QLINGSSAAT PPPPNSNSST SCNRACGGVS IPFPFGIGKD CYLNGWYEVI CNTSTSGSSG TTVPFLSRIN SEVVNISLPD GKKLYGVVHI KGPVTSLGCS SSSSSSQVSE MSLPNLNVTG RGSPYFLTDE NCLVMVGCGT KALMKDIESE ILGCESSCED SKSSEEVTNS KCDGYKCCQA RIPLERPQVI GINIENTSAT RGKEGCSVAF LTNKRYAPMN VTEPEQFHAG GYAVVELGWY FDTSDSRYRN PLGCRNMTRY SSYSSFDKCS CEYDYFSGMS YRICYCNYGY TGNPYLRHGC IDIDECEGHH NCGEGTCVNM PGTHSCEPKI TKPEKASVLQ GVLISLGVLL FVLGILGLYK FIKKRTRIIR NKNFFKRNGG LLLKQQLITK NGNVDMSRIF SSKELKKATD NFSMNRVLGQ GGQGTVYKGM LAEGRIVAVK RSKVVGEGKM EEFINEVVLL SQINHRNIVK LLGCCLETEV PVLVYEYIPN GDLFKRLHEK SESNDYTMTW EVRLRIAIEI AGALSYMHSA ASIPIYHRDI KTTNILLDEK YRAKVSDFGT SRSITIAQTH LTTLVAGTFG YMDPEYFLSS QYTDKSDVYS FGVVLVELIT GEKPLSRKRI GN