WAKLE_ARATH » Wall-associated receptor kinase-like 5

WAKLE_ARATH » Wall-associated receptor kinase-like 5
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
WAKLE_ARATH » Wall-associated receptor kinase-like 5 »
Hydrophobic Thickness 40.4 ± 2.4 Å
Tilt Angle 2 ± 1°
ΔGtransfer -56.3 kcal/mol
ΔGfold -21.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 354-382 (354-385)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 39-160, Wall-associated receptor kinase galacturonan-binding

AA: 189-289, Wall-associated kinase

AA: 432-701, PDBID: 3TL8, Subunit A, Seq Identity:45%, Protein kinase domain

UniProt annotation for WAKLE_ARATH » Wall-associated receptor kinase-like 5
FUNCTION: Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. May be involved in plant"s response to pathogen infection.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Preferentially expressed in roots and flowers.

INDUCTION: Induced by INA and wounding.

DOMAIN: The EGF-like region is specific to this family of proteins and seems to consist of the C-terminal of an EGF-like domain fused to the N-terminal of another one.

UniProt features for WAKLE_ARATH » Wall-associated receptor kinase-like 5
SIGNAL 1 26 Potential.
CHAIN 27 731 Wall-associated receptor kinase-like 5.
DOMAIN 432 705 Protein kinase.
REGION 285 342 Atypical EGF-like.
ACT_SITE 557 557 Proton acceptor (By similarity).
DISULFID 287 300 By similarity.
DISULFID 322 333 By similarity.
DISULFID 328 342 By similarity.
Amino Acid Sequence for WAKLE_ARATH » Wall-associated receptor kinase-like 5
MKTKTYRFVC LVASVLTLQL MNGSSAATPP PPPNSKNSST SCNRTCGGIS IPFPFGIGGK DCYLNGWYEV VCNATTSGSS GTTVPFLSRI NREVVNISLP EGNNEQYGVV HIKGPVTSLG CSSNTSQVPQ KSLPDLNVTG KGSPYFITDE NRLVAVGCGT KALMTDIESE ILGCESSCKD SKSSQEVTNL LCDGYKCCQA RIPVERPQAV GVNIESSGGD GCKVAFLSSK RYSPSNVTIP EQFHAGGYVV VELGWYFATT DSRFRNPLGC INLTYSGSYL SGDSCLCEYG YFSEMSYRNC YCSLGFTGNP YLRGGCIDND DCKGPNICEE GTCVNVPGGY RCDPKPKIIK PAKPLVLQGV LLGLMGLLFL VVGTLGLIIF IKKRRRIISS RKFFKRNGGL LLKQQLTTTN DGNVDMSRLF SSEELKKATD NFSVKRVLGK GSQGTVYKGM MVDGKIIAVK RSKVVDEDKL EKFINEIILL SQINHRNIVK LIGCCLETEV PILVYEYIPN GDMFKRLHDE SDDYAMTWEV RLRIAIEIAG ALTYMHSAAS FPIYHRDIKT TNILLDEKYG AKVSDFGTSR SVTIDQTHLT TMVAGTFGYM DPEYFLSSQY TDKSDVYSFG VVLVELITGE KPLSRIRSEE GRGLATHFLE AMKENRVIDI IDIRIKEESK LDQLMAVAKL ARKCLSRKGI KRPNMREASL ELERIRSSPE DLEAHIENDD EEDQVMEISR E