WAKLD_ARATH » Wall-associated receptor kinase-like 4

WAKLD_ARATH » Wall-associated receptor kinase-like 4
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
WAKLD_ARATH » Wall-associated receptor kinase-like 4 »
Hydrophobic Thickness 35.6 ± 1.4 Å
Tilt Angle 0 ± 1°
ΔGtransfer -54.8 kcal/mol
ΔGfold -17.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 349-374 (349-378)
Pathways none
PDB none
OPM none
Complexes none
Interactions

UBC34, Complex: WAKLD:UBC34

Domains

AA: 31-144, Wall-associated receptor kinase galacturonan-binding

AA: 174-282, Wall-associated kinase

AA: 424-694, PDBID: 3OMV, Subunit A, Seq Identity:43%, Protein tyrosine kinase

UniProt annotation for WAKLD_ARATH » Wall-associated receptor kinase-like 4
FUNCTION: Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Plays a role in plant mineral nutrients response.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Expressed in the whole plant. Detected in root-shoot junctions and lateral root initiation sites.

INDUCTION: Induced by INA. Up-regulated in vascular tissues after Na(+), K(+), Cu(2+), Ni(2+) or Zn(2+) exposure.

DOMAIN: The EGF-like region is specific to this family of proteins and seems to consist of the C-terminal of an EGF-like domain fused to the N-terminal of another one.

UniProt features for WAKLD_ARATH » Wall-associated receptor kinase-like 4
SIGNAL 1 26 Potential.
CHAIN 27 761 Wall-associated receptor kinase-like 4.
DOMAIN 424 697 Protein kinase.
REGION 278 339 Atypical EGF-like.
ACT_SITE 549 549 Proton acceptor (By similarity).
DISULFID 280 293 By similarity.
DISULFID 316 330 By similarity.
DISULFID 325 339 By similarity.
Amino Acid Sequence for WAKLD_ARATH » Wall-associated receptor kinase-like 4
MKKETQNLQC IPLVISVLSL FGVSSARKPP YLCNRVCGGI SIPFPFGIGG KECYLNPWYE VVCNTTTSVP FLSRINRELV NIYLPDPTEY YSNGVVHIKG PVTSSGCSTG TSQPLTPQPL NVAGQGSPYF LTDKNLLMAV GCNVKAVMMD VKSQIIGCES SCDERNSSSQ VVRNKICSGN KCCQTRIPEG QPQVIGVNIE IPENKNTTEG GCKVAFLTSN KYSSLNVTEP EEFHSDGYAV VELGWYFDTS DSRVLSPIGC MNVSDASQDG GYGSETICVC SYGYFSGFSY RSCYCNSMGY AGNPFLPGGC VDIDECKLEI GRKRCKDQSC VNKPGWFTCE PKKPGQIKPV FQGVLIGSAL LLFAFGIFGL YKFIKKQRRS SRMRVFFRRN GGMLLKQQLA RKEGNVEMSK IFSSNELEKA TDNFNTNRVL GQGGQGTVYK GMLVDGRIVA VKRSKAMDED KVEEFINEVV VLAQINHRNI VKLLGCCLET EVPVLVYEFV PNGDLCKRLR DECDDYIMTW EVRLHIAIEI AGALSYLHSA ASFPIYHRDI KTTNILLDEK YQVKVSDFGT SRSVTIDQTH LTTQVAGTFG YVDPEYFQSS KFTDKSDVYS FGVVLVELIT GKNPSSRVQS EENRGFAAHF VAAVKENRFL DIVDERIKDE CNLDQVMAVA KLAKRCLNRK GKKRPNMREV SVELERIRSS SYKSEIHNDD DDDDDDDDED DQAMELNIEE TWDVGMTAPA SMFNNGSPAS DVEPLVPLRT W