WAKLC_ARATH » Wall-associated receptor kinase-like 3

WAKLC_ARATH » Wall-associated receptor kinase-like 3
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
WAKLC_ARATH » Wall-associated receptor kinase-like 3 »
Hydrophobic Thickness 38.8 ± 1.0 Å
Tilt Angle 0 ± 1°
ΔGtransfer -56.7 kcal/mol
ΔGfold -20.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 350-378 (347-382)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 34-155, Wall-associated receptor kinase galacturonan-binding

AA: 183-287, Wall-associated kinase

AA: 428-695, PDBID: 3TL8, Subunit A, Seq Identity:47%, Protein kinase domain

UniProt annotation for WAKLC_ARATH » Wall-associated receptor kinase-like 3
FUNCTION: Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Preferentially expressed in roots and flowers.

DOMAIN: The EGF-like region is specific to this family of proteins and seems to consist of the C-terminal of an EGF-like domain fused to the N-terminal of another one.

UniProt features for WAKLC_ARATH » Wall-associated receptor kinase-like 3
SIGNAL 1 25 Potential.
CHAIN 26 730 Wall-associated receptor kinase-like 3.
DOMAIN 428 699 Protein kinase.
REGION 283 340 Atypical EGF-like.
ACT_SITE 553 553 Proton acceptor (By similarity).
DISULFID 285 298 By similarity.
DISULFID 320 331 By similarity.
DISULFID 326 340 By similarity.
Amino Acid Sequence for WAKLC_ARATH » Wall-associated receptor kinase-like 3
MKTKTYNFRY IVASVLTLLM NGSSAATPPN SNSSSSCNRT FGGISIPFPF GIGGKDCYLN SWYEVVCNST TSGSCKTVPF LTRINREVVN ISLPKSDFFS PYGVVHIKGP VTSLGCSSNI SQGLQKTLPD LNITGRGSPY FLTDENRLVA VGCGTKALMT DIESEILGCE SSCKDTKSNE VGNSLCNGYK CCQARLPVER PQAVGVNIES NNDTRGEGCK AAFLTSMKYF PSNITKPEWF QADGYAVVEL GWYFDTSDSR FRNPLGCTNL TRSSGSYFLT DICLCRYGYF SRMSYRSCYC GSGYRGNPYI RGGCIDIDEC EVPNKCGEDT CVNMAGRYSC VPKITKPAKL AHVLRGVLIG LLGLLFFVIG IFGLYKFIRK RRRIIRSMKF FKRNGGLLLK QQLTTKDGSV EMSKIFSSRE LEKATDNFSI DRVLGQGGQG TVYKRMLVDG SIVAVKRSKV VDEDKMEEFI NEIVLLSQIN HRNIVKLLGC CLETEVPILV YEYIPNGDLF KRLHDEYDDY MMTWEVRLRI AVEIAGALSY MHSAASFPIF HRDIKTTNIL LDEKYRAKIS DFGTSRSVAT DQTHLTTLVA GTFGYMDPEY FLSSQYTHKS DVYSFGVVLV ELITGEKPMS RVRSEEGIGL ATYFLEAMKE NRAVDIIDIR IKDESKQVMA VAKLARRCLN RKGNKRPNMR EVSIKLERIR SSPKDLDVHT ENEEEEEEDQ LMEINRIYDS