WAK5_ARATH » Wall-associated receptor kinase 5

WAK5_ARATH » Wall-associated receptor kinase 5
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
WAK5_ARATH » Wall-associated receptor kinase 5 »
Hydrophobic Thickness 27.6 ± 2.8 Å
Tilt Angle 7 ± 6°
ΔGtransfer -45.3 kcal/mol
ΔGfold -21.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 330-354 (326-361)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 26-126, Wall-associated receptor kinase galacturonan-binding

AA: 279-320, PDBID: 1UZJ, Subunit B, Seq Identity:46%, Calcium-binding EGF domain

AA: 408-678, PDBID: 1FMK, Subunit A, Seq Identity:42%, Protein tyrosine kinase

UniProt annotation for WAK5_ARATH » Wall-associated receptor kinase 5
FUNCTION: Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Predominantly expressed in green tissues such as stems and leaves.

INDUCTION: Induced by INA.

UniProt features for WAK5_ARATH » Wall-associated receptor kinase 5
SIGNAL 1 23 Potential.
CHAIN 24 733 Wall-associated receptor kinase 5.
DOMAIN 231 278 EGF-like 1.
DOMAIN 279 321 EGF-like 2; calcium-binding (Potential).
DOMAIN 408 691 Protein kinase.
ACT_SITE 533 533 Proton acceptor (By similarity).
DISULFID 235 250 By similarity.
DISULFID 244 261 By similarity.
DISULFID 263 277 By similarity.
DISULFID 283 296 By similarity.
DISULFID 290 305 By similarity.
DISULFID 307 320 By similarity.
Amino Acid Sequence for WAK5_ARATH » Wall-associated receptor kinase 5
MKVHSLFLMA IFFYLAYTQL VKAQPRDDCQ TRCGDVPIDY PFGISTGCYY PGDDSFNITC EEDKPNVLSN IEVLNFNHSG QLRGLIPRST VCYDQQTNND FESLWFRLDN LSFSPNNKFT LVGCNAWALL STFGIQNYST GCMSLCDTPP PPNSKCNGVG CCRTEVSIPL DSHRIETQPS RFENMTSVEH FNPCSYAFFV EDGMFNFSSL EDLKDLRNVT RFPVLLDWSI GNQTCEQVVG RNICGGNSTC FDSTRGKGYN CKCLQGFDGN PYLSDGCQDI NECTTRIHNC SDTSTCENTL GSFHCQCPSG SDLNTTTMSC IDTPKEEPKY LGWTTVLLGT TIGFLIILLT ISYIQQKMRH RKNTELRQQF FEQNGGGMLI QRLSGAGPSN VDVKIFTEEG MKEATDGYNE SRILGQGGQG TVYKGILQDN SIVAIKKARL GDRSQVEQFI NEVLVLSQIN HRNVVKLLGC CLETEVPLLV YEFISSGTLF DHLHGSMFDS SLTWEHRLRI AIEVAGTLAY LHSYASIPII HRDVKTANIL LDENLTAKVA DFGASRLIPM DQEQLTTMVQ GTLGYLDPEY YNTGLLNEKS DVYSFGVVLM ELLSGEKALC FERPQSSKHL VSYFVSAMKE NRLHEIIDGQ VMNEYNQREI QESARIAVEC TRIMGEERPS MKEVAAELEA LRVKTTKHQW SDQYPKEVEH LLGVQILSTQ GDTSSIGYDS IQNVTRLDIE TGR