WAK3_ARATH » Wall-associated receptor kinase 3

WAK3_ARATH » Wall-associated receptor kinase 3
Magnify WAK3_ARATH » Wall-associated receptor kinase 3Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
WAK3_ARATH » Wall-associated receptor kinase 3 »
Hydrophobic Thickness 34.6 ± 1.2 Å
Tilt Angle 5 ± 4°
ΔGtransfer -28.0 kcal/mol
ΔGfold -25.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 341-362 (336-370)
Pathways none
PDB none
OPM none
Complexes none
Interactions

ABAH2, Complex: ABAH2:WAK3

ACCR2, Complex: ACCR2:WAK3

ANX2, Complex: ANX2:WAK3

ATL16, Complex: ATL16:WAK3

ATL1, Complex: ATL1:WAK3

ATL41, Complex: ATL41:WAK3

ATL4, Complex: ATL4:WAK3

ATL70, Complex: ATL70:WAK3

ATL75, Complex: ATL75:WAK3

ATL78, Complex: ATL78:WAK3

ATL79, Complex: ATL79:WAK3

B120, Complex: B120:WAK3

BET12, Complex: WAK3:BET12

BETL2, Complex: WAK3:BETL2

C71BJ, Complex: C71BJ:WAK3

C76C1, Complex: C76C1:WAK3

C83A1, Complex: C83A1:WAK3

C85A1, Complex: C85A1:WAK3

CASP, Complex: CASP:WAK3

CRK11, Complex: CRK11:WAK3

CRK13, Complex: CRK13:WAK3

CRK14, Complex: CRK14:WAK3

CRK26, Complex: CRK26:WAK3

CRK2, Complex: CRK2:WAK3

CRK30, Complex: CRK30:WAK3

CRK31, Complex: CRK31:WAK3

CRK32, Complex: CRK32:WAK3

CRK33, Complex: CRK33:WAK3

CRK39, Complex: CRK39:WAK3

CRK40, Complex: WAK3:CRK40

CRK42, Complex: CRK42:WAK3

CX5C2, Complex: CX5C2:WAK3

ERL1, Complex: ERL1:WAK3

EXS, Complex: EXS:WAK3

FEI1, Complex: FEI1:WAK3

FEI2, Complex: FEI2:WAK3

FH10, Complex: FH10:WAK3

FH9, Complex: FH9:WAK3

GOS12, Complex: GOS12:WAK3

LK111, Complex: LK111:WAK3

LRK15, Complex: LRK15:WAK3

LRK17, Complex: LRK17:WAK3

LRK21, Complex: LRK21:WAK3

LRK32, Complex: LRK32:WAK3

LRK42, Complex: LRK42:WAK3

LRK53, Complex: LRK53:WAK3

LRK54, Complex: LRK54:WAK3

LRK55, Complex: LRK55:WAK3

LRK56, Complex: LRK56:WAK3

LRK57, Complex: LRK57:WAK3

LRK62, Complex: LRK62:WAK3

LRK82, Complex: LRK82:WAK3

LRK91, Complex: LRK91:WAK3

LYK5, Complex: LYK5:WAK3

MEM12, Complex: MEM12:WAK3

NDUB8, Complex: NDUB8:WAK3

NICA, Complex: NICA:WAK3

NPS13, Complex: NPS13:WAK3

OST48, Complex: OST48:WAK3

P24B2, Complex: P24B2:WAK3

P24B3, Complex: P24B3:WAK3

P24D3, Complex: P24D3:WAK3

P24DA, Complex: P24DA:WAK3

PAM74, Complex: WAK3:PAM74

PCR5, Complex: PCR5:WAK3

PCR6, Complex: PCR6:WAK3

PERK4, Complex: PERK4:WAK3

PERK8, Complex: PERK8:WAK3

PHF1, Complex: PHF1:WAK3

RLK90, Complex: RLK90:WAK3

SBIR1, Complex: SBIR1:WAK3

SC61B, Complex: SC61B:WAK3

SD113, Complex: SD113:WAK3

SRF6, Complex: SRF6:WAK3

SRF8, Complex: SRF8:WAK3

TGD2, Complex: TGD2:WAK3

UBC32, Complex: WAK3:UBC32

UBC34, Complex: WAK3:UBC34

VSR1, Complex: VSR1:WAK3

WAK4, Complex: WAK4:WAK3

WAKLG, Complex: WAKLG:WAK3

WAKLI, Complex: WAKLI:WAK3

WAKLJ, Complex: WAKLJ:WAK3

WAKLN, Complex: WAKLN:WAK3

WAKLO, Complex: WAKLO:WAK3

Y1061, Complex: Y1061:WAK3

Y1124, Complex: Y1124:WAK3

Y1133, Complex: Y1133:WAK3

Y1137, Complex: Y1137:WAK3

Y1142, Complex: Y1142:WAK3

Y1497, Complex: Y1497:WAK3

Y1634, Complex: Y1634:WAK3

Y1677, Complex: Y1677:WAK3

Y1719, Complex: Y1719:WAK3

Y2232, Complex: Y2232:WAK3

Y2393, Complex: Y2393:WAK3

Y2913, Complex: Y2913:WAK3

Y3471, Complex: Y3471:WAK3

Y4245, Complex: Y4245:WAK3

Y4966, Complex: Y4966:WAK3

Y5182, Complex: Y5182:WAK3

Y5188, Complex: Y5188:WAK3

Y5241, Complex: Y5241:WAK3

Y5248, Complex: Y5248:WAK3

Y5977, Complex: Y5977:WAK3

Domains

AA: 28-130, Wall-associated receptor kinase galacturonan-binding

AA: 293-333, PDBID: 2W86, Subunit A, Seq Identity:46%, Calcium-binding EGF domain

AA: 416-685, PDBID: 2NRU, Subunit B, Seq Identity:45%, Protein tyrosine kinase

UniProt annotation for WAK3_ARATH » Wall-associated receptor kinase 3
FUNCTION: Serine/threonine-protein kinase that may function as a signaling receptor of extracellular matrix component. Binding to pectin may have significance in the control of cell expansion, morphogenesis and development.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Predominantly expressed in green tissues such as stems and leaves.

INDUCTION: Induced by INA.

UniProt features for WAK3_ARATH » Wall-associated receptor kinase 3
SIGNAL 1 23 Potential.
CHAIN 24 741 Wall-associated receptor kinase 3.
DOMAIN 245 292 EGF-like 1.
DOMAIN 293 334 EGF-like 2; calcium-binding (Potential).
DOMAIN 415 698 Protein kinase.
ACT_SITE 540 540 Proton acceptor (By similarity).
DISULFID 249 264 By similarity.
DISULFID 258 275 By similarity.
DISULFID 277 291 By similarity.
DISULFID 297 310 By similarity.
DISULFID 304 319 By similarity.
DISULFID 321 333 By similarity.
Amino Acid Sequence for WAK3_ARATH » Wall-associated receptor kinase 3
MKFQEGVFLV VIFFLAYTQL VKGQHQPRED CKLKCGNVTI EYPFGISTGC YYPGDDNFNL TCVVEEKLLL FGIIQVTNIS HSGHVSVLFE RFSECYEQKN ETNGTALGYQ LGSSFSLSSN NKFTLVGCNA LSLLSTFGKQ NYSTGCLSLC NSQPEANGRC NGVGCCTTED FSVPFDSDTF QFGSVRLRNQ VNNSLDLFNT SVYQFNPCTY AFLVEDGKFN FDSSKDLKNL RNVTRFPVAL DWSIGNQTCE QAGSTRICGK NSSCYNSTTR NGYICKCNEG YDGNPYRSEG CKDIDECISD THNCSDPKTC RNRDGGFDCK CPSGYDLNSS MSCTRPEYKR TRIFLVIIIG VLVLLLAAIC IQHATKQRKY TKLRRQFFEQ NGGGMLIQRL SGAGLSNIDF KIFTEEGMKE ATNGYDESRI LGQGGQGTVY KGILPDNTIV AIKKARLADS RQVDQFIHEV LVLSQINHRN VVKILGCCLE TEVPLLVYEF ITNGTLFDHL HGSIFDSSLT WEHRLRIAIE VAGTLAYLHS SASIPIIHRD IKTANILLDE NLTAKVADFG ASKLIPMDKE QLTTMVQGTL GYLDPEYYTT GLLNEKSDVY SFGVVLMELL SGQKALCFER PQASKHLVSY FVSATEENRL HEIIDDQVLN EDNLKEIQEA ARIAAECTRL MGEERPRMKE VAAKLEALRV EKTKHKWSDQ YPEENEHLIG GHILSAQGET SSSIGYDSIK NVAILDIETG R