VSTM4_HUMAN » V-set and transmembrane domain-containing protein 4

VSTM4_HUMAN » V-set and transmembrane domain-containing protein 4
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
VSTM4_HUMAN » V-set and transmembrane domain-containing protein 4 »
Hydrophobic Thickness 34.4 ± 1.5 Å
Tilt Angle 1 ± 16°
ΔGtransfer -23.3 kcal/mol
ΔGfold -25.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 182-204 (175-210)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 29-142, PDBID: 1OLZ, Subunit A, Seq Identity:18%, Immunoglobulin domain

UniProt annotation for VSTM4_HUMAN » V-set and transmembrane domain-containing protein 4
FUNCTION: Peptide Lv enhances L-type voltage-gated calcium channel (L-VGCC) currents in retinal photoreceptors.
UniProt features for VSTM4_HUMAN » V-set and transmembrane domain-containing protein 4
SIGNAL 1 23 Potential.
CHAIN 24 320 V-set and transmembrane domain-containing protein 4.
DOMAIN 24 155 Ig-like.
DISULFID 46 127 By similarity.
Amino Acid Sequence for VSTM4_HUMAN » V-set and transmembrane domain-containing protein 4
MRLLALAAAA LLARAPAPEV CAALNVTVSP GPVVDYLEGE NATLLCHVSQ KRRKDSLLAV RWFFAHSFDS QEALMVKMTK LRVVQYYGNF SRSAKRRRLR LLEEQRGALY RLSVLTLQPS DQGHYVCRVQ EISRHRNKWT AWSNGSSATE MRVISLKASE ESSFEKTKET WAFFEDLYVY AVLVCCVGIL SILLFMLVIV WQSVFNKRKS RVRHYLVKCP QNSSGETVTS VTSLAPLQPK KGRRQKEKPD IPPAVPAKAP IAPTFHKPKL LKPQRKVTLP KIAEENLTYA ELELIKPHRA AKGAPTSTVY AQILFEENKL