VSR4_ARATH » Vacuolar-sorting receptor 4

VSR4_ARATH » Vacuolar-sorting receptor 4
Magnify VSR4_ARATH » Vacuolar-sorting receptor 4Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
VSR4_ARATH » Vacuolar-sorting receptor 4 » AtVSR4; BP80-like protein a;AtBP80a; Epidermal growth factor receptor-like protein 2b;AtELP2b;
Hydrophobic Thickness 34.8 ± 2.4 Å
Tilt Angle 7 ± 5°
ΔGtransfer -33.7 kcal/mol
ΔGfold -21.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 568-590 (564-596)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 61-164, PDBID: 4TJV, Subunit A, Seq Identity:56%, PA domain

AA: 498-520, PDBID: 1HJ7, Subunit A, Seq Identity:46%, Complement Clr-like EGF-like

UniProt annotation for VSR4_ARATH » Vacuolar-sorting receptor 4
FUNCTION: Vacuolar-sorting receptor (VSR) involved in clathrin- coated vesicles sorting from Golgi apparatus to vacuoles.

TISSUE SPECIFICITY: Expressed at low levels in seeds, seedlings, roots, stems, leaves, flowers and siliques.

DOMAIN: The tyrosine-based internalization signal may be involved in trafficking at the TGN.

UniProt features for VSR4_ARATH » Vacuolar-sorting receptor 4
SIGNAL 1 24 Potential.
CHAIN 25 628 Vacuolar-sorting receptor 4.
DOMAIN 56 168 PA.
DOMAIN 416 466 EGF-like 1.
DOMAIN 469 516 EGF-like 2.
DOMAIN 517 559 EGF-like 3; calcium-binding (Potential).
MOTIF 610 613 Tyrosine-based internalization motif (By similarity).
DISULFID 420 438 By similarity.
DISULFID 427 447 By similarity.
DISULFID 449 465 By similarity.
DISULFID 473 493 By similarity.
DISULFID 480 501 By similarity.
DISULFID 503 515 By similarity.
DISULFID 545 558 By similarity.
Amino Acid Sequence for VSR4_ARATH » Vacuolar-sorting receptor 4
MKQLLCYLPW LLLLSLVVSP FNEARFVVEK NSLSVTSPES IKGTHDSAIG NFGIPQYGGS MAGTVVYPKE NQKSCKEFSD FSISFKSQPG ALPTFLLVDR GDCFFALKVW NAQKAGASAV LVADNVDEPL ITMDTPEEDV SSAKYIENIT IPSALVTKGF GEKLKKAISG GDMVNLNLDW REAVPHPDDR VEYELWTNSN DECGVKCDML MEFVKDFKGA AQILEKGGFT QFRPHYITWY CPHAFTLSRQ CKSQCINKGR YCAPDPEQDF SSGYDGKDVV VENLRQLCVY KVANETGKPW VWWDYVTDFQ IRCPMKEKKY NKDCAESVIK SLGIDSRKID KCMGDPDADL DNPVLKEEQD AQVGKGTRGD VTILPTLVVN NRQYRGKLEK SAVLKALCSG FEESTEPAIC LSTDMETNEC LDNNGGCWQD KSANITACKD TFRGKVCVCP IVDGVRFKGD GYSHCEPSGP GRCTINNGGC WHEERDGHAF SACVDKDSVK CECPPGFKGD GVKKCEDINE CKEKKACQCP ECSCKNTWGS YECSCSGDLL YMRDHDTCIS KTGSQVKSAW AAVWLIMLSL GLAAAGAYLV YKYRLRQYMD SEIRAIMAQY MPLDSQPEVP NHTNDERA