VSR2_ARATH » Vacuolar-sorting receptor 2

VSR2_ARATH » Vacuolar-sorting receptor 2
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Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
VSR2_ARATH » Vacuolar-sorting receptor 2 » AtVSR2; BP80-like protein c;AtBP80c; Epidermal growth factor receptor-like protein 4;AtELP4;
Hydrophobic Thickness 29.2 ± 2.4 Å
Tilt Angle 1 ± 0°
ΔGtransfer -37.8 kcal/mol
ΔGfold -19.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 565-588 (565-594)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 60-163, PDBID: 4TJV, Subunit A, Seq Identity:62%, PA domain

UniProt annotation for VSR2_ARATH » Vacuolar-sorting receptor 2
FUNCTION: Vacuolar-sorting receptor (VSR) involved in clathrin- coated vesicles sorting from Golgi apparatus to vacuoles.

TISSUE SPECIFICITY: Expressed only in flowers.

DOMAIN: The tyrosine-based internalization signal may be involved in trafficking at the TGN.

UniProt features for VSR2_ARATH » Vacuolar-sorting receptor 2
SIGNAL 1 19 Potential.
CHAIN 20 625 Vacuolar-sorting receptor 2.
DOMAIN 55 167 PA.
DOMAIN 415 465 EGF-like 1.
DOMAIN 468 515 EGF-like 2.
DOMAIN 516 558 EGF-like 3; calcium-binding (Potential).
MOTIF 608 611 Tyrosine-based internalization motif (By similarity).
DISULFID 419 437 By similarity.
DISULFID 426 446 By similarity.
DISULFID 448 464 By similarity.
DISULFID 472 492 By similarity.
DISULFID 479 500 By similarity.
DISULFID 502 514 By similarity.
DISULFID 544 557 By similarity.
Amino Acid Sequence for VSR2_ARATH » Vacuolar-sorting receptor 2
MRTTNVWLVV IVWVTVGWSS CTGRFVVEKN NLRVTSPESI RGVYECALGN FGVPQYGGSM SGAVVYPKTN QKACKNFDDF EISFRSRVAG LPTFVLVDRG DCYFTLKAWN AQRAGAATIL VADNRPEQLI TMDAPEDETS DADYLQNITI PSALVSRSLG SAIKTAIAHG DPVHISLDWR EALPHPNDRV AYELWTNSND ECGSKCDAQI RFLKRFKGAA QILEKGGYTR FTPHYITWYC PEAFLASRQC KTQCINGGRY CAPDPEQDFS RGYNGKDVII QNLRQACFFR VTNESGKPWL WWDYVTDFAI RCPMKEEKYN KKCADQVIQS LGVDVKKIDK CIGDIDANAE NPVLKEEQVA QVGKGSRGDV TILPTIVINN RQYRGKLQRS AVLKALCSGF RETTEPPICL TEDIETNECL QNNGGCWEDK TTNITACRDT FRGRVCQCPI VQGVKFLGDG YTHCEASGAL RCGINNGGCW KQTQMGKTYS ACRDDHSKGC KCPPGFIGDG LKECKDVNEC EEKTACQCRD CKCKNTWGSY ECSCSGSLLY IREHDICINR DARGDFSWGV IWIIIMGLGA AALGAYTVYK YRIRTYMDSE IRAIMAQYMP LDNNPNTQLS SQLEL