VSIG8_HUMAN » V-set and immunoglobulin domain-containing protein 8

VSIG8_HUMAN » V-set and immunoglobulin domain-containing protein 8
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
VSIG8_HUMAN » V-set and immunoglobulin domain-containing protein 8 »
Hydrophobic Thickness 35.2 ± 2.2 Å
Tilt Angle 2 ± 1°
ΔGtransfer -35.3 kcal/mol
ΔGfold -15.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 261-286 (257-288)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 27-143, PDBID: 5DZO, Subunit A, Seq Identity:28%, Immunoglobulin V-set domain

AA: 148-243, PDBID: 1RY7, Subunit B, Seq Identity:26%, Immunoglobulin domain

UniProt features for VSIG8_HUMAN » V-set and immunoglobulin domain-containing protein 8
SIGNAL 1 21 Potential.
CHAIN 22 414 V-set and immunoglobulin domain- containing protein 8.
DOMAIN 22 141 Ig-like V-type 1.
DOMAIN 146 257 Ig-like V-type 2.
DISULFID 44 126 By similarity.
DISULFID 167 239 By similarity.
Amino Acid Sequence for VSIG8_HUMAN » V-set and immunoglobulin domain-containing protein 8
MRVGGAFHLL LVCLSPALLS AVRINGDGQE VLYLAEGDNV RLGCPYVLDP EDYGPNGLDI EWMQVNSDPA HHRENVFLSY QDKRINHGSL PHLQQRVRFA ASDPSQYDAS INLMNLQVSD TATYECRVKK TTMATRKVIV TVQARPAVPM CWTEGHMTYG NDVVLKCYAS GGSQPLSYKW AKISGHHYPY RAGSYTSQHS YHSELSYQES FHSSINQGLN NGDLVLKDIS RADDGLYQCT VANNVGYSVC VVEVKVSDSR RIGVIIGIVL GSLLALGCLA VGIWGLVCCC CGGSGAGGAR GAFGYGNGGG VGGGACGDLA SEIREDAVAP GCKASGRGSR VTHLLGYPTQ NVSRSLRRKY APPPCGGPED VALAPCTAAA ACEAGPSPVY VKVKSAEPAD CAEGPVQCKN GLLV