VSIG2_HUMAN » V-set and immunoglobulin domain-containing protein 2

VSIG2_HUMAN » V-set and immunoglobulin domain-containing protein 2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
VSIG2_HUMAN » V-set and immunoglobulin domain-containing protein 2 » Cortical thymocyte-like protein;CT-like protein;
Hydrophobic Thickness 38.4 ± 1.8 Å
Tilt Angle 0 ± 1°
ΔGtransfer -49.9 kcal/mol
ΔGfold -18.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 242-266 (237-273)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 27-142, PDBID: 3KAA, Subunit A, Seq Identity:29%, Immunoglobulin V-set domain

AA: 142-221, PDBID: 4X9H, Subunit B, Seq Identity:31%, Immunoglobulin domain

UniProt annotation for VSIG2_HUMAN » V-set and immunoglobulin domain-containing protein 2
TISSUE SPECIFICITY: Highly expressed in stomach, colon, prostate, trachea and thyroid glands and weakly in bladder and lung.
UniProt features for VSIG2_HUMAN » V-set and immunoglobulin domain-containing protein 2
SIGNAL 1 23
CHAIN 24 327 V-set and immunoglobulin domain- containing protein 2.
DOMAIN 24 137 Ig-like V-type.
DOMAIN 144 233 Ig-like C2-type.
DISULFID 45 121 By similarity.
DISULFID 166 217 By similarity.
Amino Acid Sequence for VSIG2_HUMAN » V-set and immunoglobulin domain-containing protein 2
MAELPGPFLC GALLGFLCLS GLAVEVKVPT EPLSTPLGKT AELTCTYSTS VGDSFALEWS FVQPGKPISE SHPILYFTNG HLYPTGSKSK RVSLLQNPPT VGVATLKLTD VHPSDTGTYL CQVNNPPDFY TNGLGLINLT VLVPPSNPLC SQSGQTSVGG STALRCSSSE GAPKPVYNWV RLGTFPTPSP GSMVQDEVSG QLILTNLSLT SSGTYRCVAT NQMGSASCEL TLSVTEPSQG RVAGALIGVL LGVLLLSVAA FCLVRFQKER GKKPKETYGG SDLREDAIAP GISEHTCMRA DSSKGFLERP SSASTVTTTK SKLPMVV