VAMP5_HUMAN » Vesicle-associated membrane protein 5

VAMP5_HUMAN » Vesicle-associated membrane protein 5
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
VAMP5_HUMAN » Vesicle-associated membrane protein 5 » VAMP-5; Myobrevin;
Hydrophobic Thickness 36.4 ± 3.2 Å
Tilt Angle 4 ± 3°
ΔGtransfer -32.3 kcal/mol
ΔGfold -25.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 69-93 (64-93)
Pathways

SNARE interactions in vesicular transport (KEGG)

PDB none
OPM none
Complexes none
Interactions

STX16, Complex: STX16:VAMP5

STX1A, Complex: STX1A:VAMP5

STX4, Complex: STX4:VAMP5

Domains

AA: 4-90, PDBID: 1KIL, Subunit A, Seq Identity:37%, Synaptobrevin

UniProt annotation for VAMP5_HUMAN » Vesicle-associated membrane protein 5
FUNCTION: May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking.

INDUCTION: During myogenesis.

UniProt features for VAMP5_HUMAN » Vesicle-associated membrane protein 5
CHAIN 1 116 Vesicle-associated membrane protein 5.
DOMAIN 5 65 v-SNARE coiled-coil homology.
Amino Acid Sequence for VAMP5_HUMAN » Vesicle-associated membrane protein 5
MAGIELERCQ QQANEVTEIM RNNFGKVLER GVKLAELQQR SDQLLDMSST FNKTTQNLAQ KKCWENIRYR ICVGLVVVGV LLIILIVLLV VFLPQSSDSS SAPRTQDAGI ASGPGN