USE1_HUMAN » Vesicle transport protein USE1

USE1_HUMAN » Vesicle transport protein USE1
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
USE1_HUMAN » Vesicle transport protein USE1 » Putative MAPK-activating protein PM26;USE1-like protein;p31;
Hydrophobic Thickness 31.6 ± 2.6 Å
Tilt Angle 22 ± 18°
ΔGtransfer -28.9 kcal/mol
ΔGfold -23.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 231-254 (230-255)
Pathways

SNARE interactions in vesicular transport (KEGG)

PDB none
OPM none
Complexes none
Interactions

A4, Complex: USE1:A4, PubMed

CREB3, Complex: USE1:CREB3

Domains

AA: 5-255, Membrane fusion protein Use1

UniProt annotation for USE1_HUMAN » Vesicle transport protein USE1
FUNCTION: SNARE that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.

SUBUNIT: Component of a SNARE complex consisting of STX18, USE1L, BNIP1/SEC20L and SEC22B. Interacts directly with STX18.

UniProt features for USE1_HUMAN » Vesicle transport protein USE1
CHAIN 1 259 Vesicle transport protein USE1.
COILED 152 231 Potential.
Amino Acid Sequence for USE1_HUMAN » Vesicle transport protein USE1
MAASRLELNL VRLLSRCEAM AAEKRDPDEW RLEKYVGALE DMLQALKVHA SKPASEVINE YSWKVDFLKG MLQAEKLTSS SEKALANQFL APGRVPTTAR ERVPATKTVH LQSRARYTSE MRSELLGTDS AEPEMDVRKR TGVAGSQPVS EKQSAAELDL VLQRHQNLQE KLAEEMLGLA RSLKTNTLAA QSVIKKDNQT LSHSLKMADQ NLEKLKTESE RLEQHTQKSV NWLLWAMLII VCFIFISMIL FIRIMPKLK