UBX3_YEAST » UBX domain-containing protein 3

UBX3_YEAST » UBX domain-containing protein 3
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
UBX3_YEAST » UBX domain-containing protein 3 »
Hydrophobic Thickness 30.4 ± 3.7 Å
Tilt Angle 5 ± 3°
ΔGtransfer -17.9 kcal/mol
ΔGfold -10.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 54-75 (48-78)
Pathways none
PDB none
OPM none
Complexes none
Interactions

FAR10, Complex: UBX3:FAR10

NCE1, Complex: NCE1:UBX3

PNT1, Complex: UBX3:PNT1

SEC11, Complex: SEC11:UBX3

YP168, Complex: YP168:UBX3

Domains

AA: 355-452, PDBID: 1I42, Subunit A, Seq Identity:24%, UBX domain

UniProt annotation for UBX3_YEAST » UBX domain-containing protein 3
FUNCTION: Involved in CDC48-dependent protein degradation through the ubiquitin/proteasome pathway. Involved in delivery of substrates to the 26S proteasome. Also required for membrane fusion (By similarity).

SUBUNIT: Interacts with CDC48.

MISCELLANEOUS: Present with 233 molecules/cell in log phase SD medium.

UniProt features for UBX3_YEAST » UBX domain-containing protein 3
CHAIN 1 455 UBX domain-containing protein 3.
DOMAIN 356 455 UBX.
Amino Acid Sequence for UBX3_YEAST » UBX domain-containing protein 3
MDIFRHTFGN NDDSFIRIPG AFREEPPADL NGRTEDQNSN TNEPTQSRDG RLKSILHFLF QAPLIVLYYL LNFIVRSSRL LKPLLRLHGF YQRKHNRLLD HSSQLHRLLE NLENEAQAVT CSEGNGNNDD GSNTDSTSNN ESSGVQFSFG SLYNPENGTF SKSIMQNSYT ELLDACSEQV KFGVIYLHDP LLDNHMDYVN KILCSEAFVN MIRKYQVLLW YGDVTTSEGL QVSNALKIRQ YPLLGIISLK AEKKIELIAR VEGSISNYKA QDLEAIFSKN YSRLIQLRQQ RQNIEMQRLI RQQQDSRYQD SLRRDQQRES ERLEQTQREQ MEREHQRIEN QWLLWRKSQL KPEPSSDKDA SKVAIRLENG QRLVRKFDAS LPTEEIYAFV ELQLHDMLNS ENDTLPVYQP ANYQHQYSFK LITPVPRREL DLSTKISDVS GIYPSGNIVM ERLDE