TRBC1_HUMAN » T-cell receptor beta-1 chain C region

TRBC1_HUMAN » T-cell receptor beta-1 chain C region
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
TRBC1_HUMAN » T-cell receptor beta-1 chain C region »
Hydrophobic Thickness 27.2 ± 2.0 Å
Tilt Angle 1 ± 2°
ΔGtransfer -35.3 kcal/mol
ΔGfold -16.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 148-173 (145-175)
Pathways

Immune System (Reactome)

PDB 2axh (A/B=1-130), 2cde (B/D/F=1-130), 3dx9 (B/D=1-130), 2ial (B/D=1-130), 4gg8 (B/F=1-130), 4p46 (B=1-128), 4g8f (B=1-130), 4lcc (B=1-130), 2xna (B=1-130), 4l9l (B=1-130), 2xn9 (B=1-130), 2pyf (B=1-130), 2nw2 (B=1-130), 2cdg (B=1-130), 2cdf (B=1-130), 4g8e (B=1-130), 2bnu (B=1-130), 4iiq (B=1-130), 2po6 (D/H=1-130), 3are (D=1-130), 3arf (D=1-130), 3ard (D=1-130), 3arg (D=1-130), 3arb (D=1-130), 3he6 (D=1-130), 3tn0 (D=1-130), 2iam (D=1-130), 1ktk (E/F=5-130), 4lcw (E/H=1-130), 4nqe (E/H=1-130), 4l4v (E/H=1-130), 4nqd (E/H=1-130), 4nqc (E/H=1-130), 4l4t (E/H=1-130), 2ian (E/J/O/T=1-130), 3dxa (E/J/O=1-130), 2ak4 (E/J/P/U=1-130), 2nx5 (E/J/P/U=1-130), 4mji (E/J=1-130), 2vlr (E/J=1-130), 3kpr (E/J=1-130), 3ffc (E/J=1-130), 2f54 (E/L=6-130), 4jff (E=1-130), 4jrx (E=1-130), 4jfh (E=1-130), 4jfd (E=1-130), 4prh (E=1-130), 4pri (E=1-130), 4jfe (E=1-130), 4prp (E=1-130), 4jry (E=1-130), 3o4l (E=1-130), 1ao7 (E=1-130), 2gj6 (E=1-130), 2f53 (E=1-130), 2esv (E=1-130), 2bnr (E=1-130), 1oga (E=1-130), 1mi5 (E=1-130), 1kgc (E=1-130), 2p5e (E=1-130), 2p5w (E=1-130), 2pye (E=1-130), 3kps (E=1-130), 2vlk (E=1-130), 2vlm (E=1-130), 2vlj (E=1-130), 3d39 (E=1-130), 3d3v (E=1-130), 3hg1 (E=1-130), 1ymm (E=1-131), 1fyt (E=1-134), 1j8h (E=1-134), 4mnq (E=2-130), 4ozi (F/H=1-130), 4ozh (F/H=1-130), 4ozg (F/H=1-130), 4gg6 (F/H=1-130), 4ozf (H=1-130), 1zgl (P/R/T/V=1-131), 2nts (P=6-128)
OPM none
Complexes

MBP:DRB5:DRA:TCA:TRBC1_HUMAN

DRA:2B11:TCA:TRBC1:HEMA_HUMAN

DRA:2B11:TCA:TRBC1:TPIS_HUMAN

HEMA:ETXH:DRA:2B11:TCA:TRBC1_HUMAN

2B14:DRA:TCA:TRBC1:HEMA_HUMAN

MBP:2B1F:DRA:TCA:TRBC1_HUMAN

K7N5N2:DQA1:DQB1:GDA9:TRBC1_HUMAN

CD1D1:TCA:TRBC1:B2MG_HUMAN

TCA:TRBC1:CD1D:B2MG_HUMAN

TCA:TRBC1_HUMAN

CTG1B:TCA:TRBC1:1A02:B2MG_HUMAN

M1:TCA:TRBC1:1A02:B2MG_HUMAN

ICP27:Q8WLS4:TCA:TRBC1:1A02:B2MG_HUMAN

TCA:TRBC1:MAR1:1A02:B2MG_HUMAN

A0A585:H2RG00:K7N5N2:TERT:TRBC1:1A02:B2MG_HUMAN

TAX:TRBC1:1A02:B2MG_HUMAN

TCA:TRBC1:1A02:B2MG_HUMAN

EBNA3:TCA:TRBC1:1B08:B2MG_HUMAN

TCA:TRBC1:1B08:B2MG_HUMAN

BZLF1:TCA:TRBC1:1B35:B2MG_HUMAN

1B44:TCA:TRBC1:B2MG_HUMAN

EBNA6:1B44:TCA:TRBC1:B2MG_HUMAN

1B51:R4WL38:K7N5M3:TRBC1:B2MG_HUMAN

BZLF1:C5MK56:TCA:TRBC1:B2MG_HUMAN

C5MK56:TCA:TRBC1:EBNA1:B2MG_HUMAN

UL40:HLAE:TCA:TRBC1:B2MG_HUMAN

Q6P4G7:HMR1:TRBC1:B2MG_HUMAN

TCA:TRBC1_HUMAN

ETXH:TCA:TRBC1_HUMAN

Q8WLS4:TCA:TRBC1:MAR1:B2MG_HUMAN

TRBC1:TRBC1_HUMAN

Interactions

1A02, Complex: TAX:TRBC1:1A02:B2MG, PDBID: 1AO7

1B51, Complex: 1B51:R4WL38:K7N5M3:TRBC1:B2MG, PDBID: 4MJI

DQB1, Complex: K7N5N2:DQA1:DQB1:GDA9:TRBC1, PDBID: 4GG6

HMR1, Complex: HMR1:B2MG:Q6P4G7:TRBC1, PDBID: 4IIQ

TCA, Complex: DRA:2B11:TCA:TRBC1:HEMA, PDBID: 1fyt, PubMed

TRBC1, Complex: Homodimer of T-cell receptor beta-1 chain C region, PDBID: 2AXH

Domains

AA: 9-103, PDBID: 1AO7, Subunit E, Seq Identity:100%, Immunoglobulin C1-set domain

UniProt annotation for TRBC1_HUMAN » T-cell receptor beta-1 chain C region
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).
UniProt features for TRBC1_HUMAN » T-cell receptor beta-1 chain C region
CHAIN <1 177 T-cell receptor beta-1 chain C region.
DOMAIN 9 118 Ig-like.
DISULFID 31 96
Amino Acid Sequence for TRBC1_HUMAN » T-cell receptor beta-1 chain C region
EDLNKVFPPE VAVFEPSEAE ISHTQKATLV CLATGFFPDH VELSWWVNGK EVHSGVSTDP QPLKEQPALN DSRYCLSSRL RVSATFWQNP RNHFRCQVQF YGLSENDEWT QDRAKPVTQI VSAEAWGRAD CGFTSVSYQQ GVLSATILYE ILLGKATLYA VLVSALVLMA MVKRKDF