TOS2_YEAST » Protein TOS2

TOS2_YEAST » Protein TOS2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
TOS2_YEAST » Protein TOS2 » Target of SBF 2;
Hydrophobic Thickness 40.8 ± 4.0 Å
Tilt Angle 3 ± 2°
ΔGtransfer -30.9 kcal/mol
ΔGfold -24.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 37-64 (34-69)
Pathways none
PDB none
OPM none
Complexes none
Interactions

KTR6, Complex: KTR6:TOS2

VOA1, Complex: VOA1:TOS2

Domains

AA: 31-66, Transmembrane alpha-helix domain

UniProt annotation for TOS2_YEAST » Protein TOS2
FUNCTION: Seems to be involved in the anchoring of CDC24 to the membrane of polarized growth sites.

MISCELLANEOUS: Present with 56 molecules/cell in log phase SD medium.

UniProt features for TOS2_YEAST » Protein TOS2
CHAIN 1 622 Protein TOS2.
Amino Acid Sequence for TOS2_YEAST » Protein TOS2
MFSHYRYKEN SCQKREAIPD KSRVSLTFLQ KRTDSSNVTV AVAVAVPIGA IIIVLSVVLI VVYRRCKKEP SMQDFDPNFE GDLYYLPKMD SSMNSANSDS NATEKRFIYG GYDDFLQPSI ENSQSFKDYV RRINEHAPSA YNIASLASQN NSKLSVPSKH IDLSNKISFE SLENSELIVS PQHSNTGQDC DQRCDSTSNP DVNEKSSHNN DNRLKSNYTS RSGLEPQCSR EEEENIDRIR SIYNIYFEKS NSTIRSSVTS SIRRDSKLNI ATRKSVNMSS QDNPNDTTLI EQSHFGSTTV QEIDSSSSAN EEYEDATDYL QVPAPQENKN IASSVYSEVA TREKVIPESS LSLTFPPPNG LSTRITSSIY SDTVAKDHIH SAKAPVRALS EGSGQSNLTS AQQYSTYFID HCNQSNDDNY YYNYPLPLEH PQNYENIGDL PTPTQFIYST SSHSLTSFKG RPKPPKTLKH VPTARLNGTA LNPMDHPEMF YSSPTKIPST SLTKQFCTPL PYQLRQSVVM TNPSELSMKP RYKPAGSLRN LIKAQYLPGN SSTTTSSSLS QPPSTLSNAI NFRVSGLLDD TDILQPPSVG EILPFKASTE DLRKQLGTSH NYEITPYENV HV