TO203_ARATH » Mitochondrial import receptor subunit TOM20-3

TO203_ARATH » Mitochondrial import receptor subunit TOM20-3
Magnify TO203_ARATH » Mitochondrial import receptor subunit TOM20-3Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Mitochondrial outer membrane
Topologyintermembrane space
cytoplasmic side
TO203_ARATH » Mitochondrial import receptor subunit TOM20-3 » Translocase of outer membrane 20 kDa subunit 3;
Hydrophobic Thickness 28.8 ± 3.9 Å
Tilt Angle 7 ± 2°
ΔGtransfer -17.0 kcal/mol
ΔGfold -15.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 173-193 (169-195)
Pathways none
PDB 1zu2 (1-145)
OPM none
Complexes none
Interactions

NTL9, Complex: TO203:NTL9

WIP1, Complex: TO203:WIP1, PubMed

Domains

AA: 7-193, PDBID: 1ZU2, Subunit A, Seq Identity:100%, Plant specific mitochondrial import receptor subunit TOM20

UniProt annotation for TO203_ARATH » Mitochondrial import receptor subunit TOM20-3
FUNCTION: Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore.

SUBUNIT: Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 6 different proteins (TOM5, TOM6, TOM7, TOM20, TOM22/TOM9 and TOM40).

TISSUE SPECIFICITY: Expressed in roots, flowers, young cotyledons and leaves.

MISCELLANEOUS: There are four genes (TOM20-1, TOM20-2, TOM20-3 and TOM20-4) which encode mitochondrial import receptor subunits TOM20.

MISCELLANEOUS: In mammals and fungi, the transmembrane domain is located at the N-terminus while it is located at the C-terminus in plants. The overall orientation of the protein in the membrane is therefore inverted.

UniProt features for TO203_ARATH » Mitochondrial import receptor subunit TOM20-3
CHAIN 1 202 Mitochondrial import receptor subunit TOM20-3.
REPEAT 38 74 TPR 1.
REPEAT 86 119 TPR 2.
Amino Acid Sequence for TO203_ARATH » Mitochondrial import receptor subunit TOM20-3
MDTETEFDRI LLFEQIRQDA ENTYKSNPLD ADNLTRWGGV LLELSQFHSI SDAKQMIQEA ITKFEEALLI DPKKDEAVWC IGNAYTSFAF LTPDETEAKH NFDLATQFFQ QAVDEQPDNT HYLKSLEMTA KAPQLHAEAY KQGLGSQPMG RVEAPAPPSS KAVKNKKSSD AKYDAMGWVI LAIGVVAWIS FAKANVPVSP PR