TO201_ARATH » Mitochondrial import receptor subunit TOM20-1

TO201_ARATH » Mitochondrial import receptor subunit TOM20-1
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Topology in Mitochondrial outer membrane
Topologyintermembrane space
cytoplasmic side
TO201_ARATH » Mitochondrial import receptor subunit TOM20-1 » Translocase of outer membrane 20 kDa subunit 1;
Hydrophobic Thickness 29.4 ± 3.8 Å
Tilt Angle 29 ± 9°
ΔGtransfer -17.9 kcal/mol
ΔGfold -16.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 163-184 (162-187)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 1-186, PDBID: 1ZU2, Subunit A, Seq Identity:62%, Plant specific mitochondrial import receptor subunit TOM20

UniProt annotation for TO201_ARATH » Mitochondrial import receptor subunit TOM20-1
FUNCTION: Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the translocation pore.

SUBUNIT: Forms part of the preprotein translocase complex of the outer mitochondrial membrane (TOM complex) which consists of at least 6 different proteins (TOM5, TOM6, TOM7, TOM20, TOM22/TOM9 and TOM40).

TISSUE SPECIFICITY: Barely detected in roots.

MISCELLANEOUS: There are four genes (TOM20-1, TOM20-2, TOM20-3 and TOM20-4) which encode mitochondrial import receptor subunits TOM20, but TOM20-1 is the only one that has not been directly identified in isolated mitochondria from cv. Columbia.

MISCELLANEOUS: In mammals and fungi, the transmembrane domain is located at the N-terminus while it is located at the C-terminus in plants. The overall orientation of the protein in the membrane is therefore inverted.

UniProt features for TO201_ARATH » Mitochondrial import receptor subunit TOM20-1
CHAIN 1 188 Mitochondrial import receptor subunit TOM20-1.
Amino Acid Sequence for TO201_ARATH » Mitochondrial import receptor subunit TOM20-1
MDKLNFFEEI RKDAEETYKL NPEDADNLMR WGEALLELSQ FQNVIDSLKM IQDAISKLED AILIDPMKHD AVWCLGNAYT SYARLTPDDT QARLNFGLAY LFFGIAVAQQ PDNQVYHKSL EMADKAPQLH TGFHKNRLLS LLGGVETLAI PSPKVVKNKK SSDEKYIVMG WVILAIGVVA CISFRKLR