TNR9_HUMAN » Tumor necrosis factor receptor superfamily member 9

TNR9_HUMAN » Tumor necrosis factor receptor superfamily member 9
Magnify TNR9_HUMAN » Tumor necrosis factor receptor superfamily member 9Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
TNR9_HUMAN » Tumor necrosis factor receptor superfamily member 9 » 4-1BB ligand receptor;CDw137;T-cell antigen 4-1BB homolog;T-cell antigen ILA;
Hydrophobic Thickness 36.0 ± 2.2 Å
Tilt Angle 0 ± 0°
ΔGtransfer -60.0 kcal/mol
ΔGfold -23.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 185-213 (185-217)
Pathways

Cytokine-cytokine receptor interaction (KEGG)

PDB none
OPM none
Complexes none
Interactions

TNFL9, Complex: TNFL9:TNR9, PubMed

TNR4, Complex: TNR4:TNR9, PubMed

Domains

AA: 48-86, PDBID: 3TJE, Subunit F, Seq Identity:39%, TNFR/NGFR cysteine-rich region

UniProt annotation for TNR9_HUMAN » Tumor necrosis factor receptor superfamily member 9
FUNCTION: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

SUBUNIT: Interacts with TRAF1, TRAF2 and TRAF3. Interacts with LRR-repeat protein 1/LRR-1.

TISSUE SPECIFICITY: Expressed on the surface of activated T-cells.

UniProt features for TNR9_HUMAN » Tumor necrosis factor receptor superfamily member 9
SIGNAL 1 23
CHAIN 24 255 Tumor necrosis factor receptor superfamily member 9.
REPEAT 24 45 TNFR-Cys 1.
REPEAT 47 86 TNFR-Cys 2.
REPEAT 87 118 TNFR-Cys 3.
REPEAT 119 159 TNFR-Cys 4.
REGION 214 255 Interaction with LRR-1.
DISULFID 28 37 By similarity.
DISULFID 31 45 By similarity.
DISULFID 48 62 By similarity.
DISULFID 65 78 By similarity.
DISULFID 68 86 By similarity.
DISULFID 88 94 By similarity.
DISULFID 99 106 By similarity.
DISULFID 102 117 By similarity.
DISULFID 121 133 By similarity.
DISULFID 139 158 By similarity.
Amino Acid Sequence for TNR9_HUMAN » Tumor necrosis factor receptor superfamily member 9
MGNSCYNIVA TLLLVLNFER TRSLQDPCSN CPAGTFCDNN RNQICSPCPP NSFSSAGGQR TCDICRQCKG VFRTRKECSS TSNAECDCTP GFHCLGAGCS MCEQDCKQGQ ELTKKGCKDC CFGTFNDQKR GICRPWTNCS LDGKSVLVNG TKERDVVCGP SPADLSPGAS SVTPPAPARE PGHSPQIISF FLALTSTALL FLLFFLTLRF SVVKRGRKKL LYIFKQPFMR PVQTTQEEDG CSCRFPEEEE GGCEL