TNMD_HUMAN » Tenomodulin

TNMD_HUMAN » Tenomodulin
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
TNMD_HUMAN » Tenomodulin » TeM; hTeM; Chondromodulin-1-like protein;ChM1L; hChM1L; Chondromodulin-I-like protein;Myodulin;Tendin;
Hydrophobic Thickness 33.6 ± 1.6 Å
Tilt Angle 3 ± 16°
ΔGtransfer -25.2 kcal/mol
ΔGfold -20.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 27-49 (17-51)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 95-185, PDBID: 2YAD, Subunit F, Seq Identity:15%, BRICHOS domain

UniProt annotation for TNMD_HUMAN » Tenomodulin
FUNCTION: May be an angiogenesis inhibitor.

TISSUE SPECIFICITY: Highly expressed in hypovascular connective tissues such as tendons. Has also strong expression in adipose tissue.

UniProt features for TNMD_HUMAN » Tenomodulin
CHAIN 1 317 Tenomodulin.
DOMAIN 93 186 BRICHOS.
Amino Acid Sequence for TNMD_HUMAN » Tenomodulin
MAKNPPENCE DCHILNAEAF KSKKICKSLK ICGLVFGILA LTLIVLFWGS KHFWPEVPKK AYDMEHTFYS NGEKKKIYME IDPVTRTEIF RSGNGTDETL EVHDFKNGYT GIYFVGLQKC FIKTQIKVIP EFSEPEEEID ENEEITTTFF EQSVIWVPAE KPIENRDFLK NSKILEICDN VTMYWINPTL ISVSELQDFE EEGEDLHFPA NEKKGIEQNE QWVVPQVKVE KTRHARQASE EELPINDYTE NGIEFDPMLD ERGYCCIYCR RGNRYCRRVC EPLLGYYPYP YCYQGGRVIC RVIMPCNWWV ARMLGRV