TMKL1_ARATH » Putative kinase-like protein TMKL1

TMKL1_ARATH » Putative kinase-like protein TMKL1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
TMKL1_ARATH » Putative kinase-like protein TMKL1 »
Hydrophobic Thickness 36.0 ± 1.6 Å
Tilt Angle 1 ± 5°
ΔGtransfer -34.8 kcal/mol
ΔGfold -14.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 300-323 (298-328)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BETL2, Complex: TMKL1:BETL2

PAM74, Complex: TMKL1:PAM74

UBC34, Complex: TMKL1:UBC34
Domains

AA: 30-69, PDBID: 3RGX, Subunit A, Seq Identity:30%, Leucine rich repeat N-terminal domain

AA: 374-649, PDBID: 2NRU, Subunit B, Seq Identity:31%, Protein tyrosine kinase
UniProt annotation for TMKL1_ARATH » Putative kinase-like protein TMKL1
FUNCTION: Does not seem to have conserved a kinase activity.

DOMAIN: The protein kinase domain is predicted to be catalytically inactive.

UniProt features for TMKL1_ARATH » Putative kinase-like protein TMKL1
SIGNAL 1 25 Potential.
CHAIN 26 674 Putative kinase-like protein TMKL1.
REPEAT 100 122 LRR 1.
REPEAT 124 146 LRR 2.
REPEAT 148 169 LRR 3.
REPEAT 173 194 LRR 4.
REPEAT 200 222 LRR 5.
REPEAT 224 244 LRR 6.
REPEAT 247 269 LRR 7.
DOMAIN 373 674 Protein kinase.
Amino Acid Sequence for TMKL1_ARATH » Putative kinase-like protein TMKL1
MGMEALRFLH VIFFFVLILH CHCGTSLSGS SDVKLLLGKI KSSLQGNSES LLLSSWNSSV PVCQWRGVKW VFSNGSPLQC SDLSSPQWTN TSLFNDSSLH LLSLQLPSAN LTGSLPREIG EFSMLQSVFL NINSLSGSIP LELGYTSSLS DVDLSGNALA GVLPPSIWNL CDKLVSFKIH GNNLSGVLPE PALPNSTCGN LQVLDLGGNK FSGEFPEFIT RFKGVKSLDL SSNVFEGLVP EGLGVLELES LNLSHNNFSG MLPDFGESKF GAESFEGNSP SLCGLPLKPC LGSSRLSPGA VAGLVIGLMS GAVVVASLLI GYLQNKKRKS SIESEDDLEE GDEEDEIGEK EGGEGKLVVF QGGENLTLDD VLNATGQVME KTSYGTVYKA KLSDGGNIAL RLLREGTCKD RSSCLPVIRQ LGRIRHENLV PLRAFYQGKR GEKLLIYDYL PNISLHDLLH ESKPRKPALN WARRHKIALG IARGLAYLHT GQEVPIIHGN IRSKNVLVDD FFFARLTEFG LDKIMVQAVA DEIVSQAKSD GYKAPELHKM KKCNPRSDVY AFGILLLEIL MGKKPGKSGR NGNEFVDLPS LVKAAVLEET TMEVFDLEAM KGIRSPMEEG LVHALKLAMG CCAPVTTVRP SMEEVVKQLE ENRPRNRSAL YSPTETRSDA ETPF