TMK1_ARATH » Probable receptor protein kinase TMK1

TMK1_ARATH » Probable receptor protein kinase TMK1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
TMK1_ARATH » Probable receptor protein kinase TMK1 »
Hydrophobic Thickness 37.2 ± 0.8 Å
Tilt Angle 0 ± 0°
ΔGtransfer -59.9 kcal/mol
ΔGfold -20.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 480-507 (478-511)
Pathways none
PDB 4hq1 (1-469)
OPM none
Complexes none
Interactions

GDU4, Complex: TMK1:GDU4

P2C70, Complex: TMK1:P2C70

Domains

AA: 25-61, PDBID: 4M7E, Subunit D, Seq Identity:29%, Leucine rich repeat N-terminal domain

AA: 103-147, PDBID: 3ZYN, Subunit A, Seq Identity:53%, Leucine rich repeat

AA: 322-360, PDBID: 3RGX, Subunit A, Seq Identity:27%, Leucine rich repeat N-terminal domain

AA: 588-865, PDBID: 3TL8, Subunit A, Seq Identity:44%, Protein kinase domain

UniProt annotation for TMK1_ARATH » Probable receptor protein kinase TMK1
FUNCTION: Probable receptor.

CATALYTIC ACTIVITY: ATP + a protein = ADP + a phosphoprotein.

TISSUE SPECIFICITY: Found in most tissues.

UniProt features for TMK1_ARATH » Probable receptor protein kinase TMK1
SIGNAL 1 23 Potential.
CHAIN 24 942 Probable receptor protein kinase TMK1.
REPEAT 89 111 LRR 1.
REPEAT 112 133 LRR 2.
REPEAT 136 157 LRR 3.
REPEAT 187 209 LRR 4.
REPEAT 210 232 LRR 5.
REPEAT 233 255 LRR 6.
REPEAT 256 277 LRR 7.
REPEAT 280 301 LRR 8.
DOMAIN 588 869 Protein kinase.
ACT_SITE 717 717 Proton acceptor (By similarity).
Amino Acid Sequence for TMK1_ARATH » Probable receptor protein kinase TMK1
MKKRRTFLLF SFTFLLLLSL SKADSDGDLS AMLSLKKSLN PPSSFGWSDP DPCKWTHIVC TGTKRVTRIQ IGHSGLQGTL SPDLRNLSEL ERLELQWNNI SGPVPSLSGL ASLQVLMLSN NNFDSIPSDV FQGLTSLQSV EIDNNPFKSW EIPESLRNAS ALQNFSANSA NVSGSLPGFL GPDEFPGLSI LHLAFNNLEG ELPMSLAGSQ VQSLWLNGQK LTGDITVLQN MTGLKEVWLH SNKFSGPLPD FSGLKELESL SLRDNSFTGP VPASLLSLES LKVVNLTNNH LQGPVPVFKS SVSVDLDKDS NSFCLSSPGE CDPRVKSLLL IASSFDYPPR LAESWKGNDP CTNWIGIACS NGNITVISLE KMELTGTISP EFGAIKSLQR IILGINNLTG MIPQELTTLP NLKTLDVSSN KLFGKVPGFR SNVVVNTNGN PDIGKDKSSL SSPGSSSPSG GSGSGINGDK DRRGMKSSTF IGIIVGSVLG GLLSIFLIGL LVFCWYKKRQ KRFSGSESSN AVVVHPRHSG SDNESVKITV AGSSVSVGGI SDTYTLPGTS EVGDNIQMVE AGNMLISIQV LRSVTNNFSS DNILGSGGFG VVYKGELHDG TKIAVKRMEN GVIAGKGFAE FKSEIAVLTK VRHRHLVTLL GYCLDGNEKL LVYEYMPQGT LSRHLFEWSE EGLKPLLWKQ RLTLALDVAR GVEYLHGLAH QSFIHRDLKP SNILLGDDMR AKVADFGLVR LAPEGKGSIE TRIAGTFGYL APEYAVTGRV TTKVDVYSFG VILMELITGR KSLDESQPEE SIHLVSWFKR MYINKEASFK KAIDTTIDLD EETLASVHTV AELAGHCCAR EPYQRPDMGH AVNILSSLVE LWKPSDQNPE DIYGIDLDMS LPQALKKWQA YEGRSDLESS TSSLLPSLDN TQMSIPTRPY GFAESFTSVD GR