TMEM9_HUMAN » Transmembrane protein 9

TMEM9_HUMAN » Transmembrane protein 9
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Topology in Lysosomal membrane
Topologylysosome lumenal side
cytoplasmic side
TMEM9_HUMAN » Transmembrane protein 9 » Dermal papilla-derived protein 4;
Hydrophobic Thickness 31.2 ± 5.2 Å
Tilt Angle 43 ± 0°
ΔGtransfer -24.0 kcal/mol
ΔGfold -19.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 83-111 (80-112)
Pathways none
PDB none
OPM none
Complexes none
Interactions

GALT6, Complex: TMEM9:GALT6, PubMed

SC22B, Complex: TMEM9:SC22B, PubMed

Domains

AA: 41-182, TMEM9

UniProt annotation for TMEM9_HUMAN » Transmembrane protein 9
FUNCTION: May be involved in intracellular transport.

SUBUNIT: Dimer.

TISSUE SPECIFICITY: Highly expressed in adrenal gland, thyroid gland, testis, ovary and prostate. Moderate expression in trachea, spinal cord, stomach, colon, small intestine and spleen. Low expression in bone marrow, lymph node, thymus and peripheral blood lymphocytes. Expression was detected in hematopoietic cell lines including those of myeloid, erythroid, B- and T-cell origin.

UniProt features for TMEM9_HUMAN » Transmembrane protein 9
SIGNAL 1 20 Potential.
CHAIN 21 183 Transmembrane protein 9.
Amino Acid Sequence for TMEM9_HUMAN » Transmembrane protein 9
MKLLSLVAVV GCLLVPPAEA NKSSEDIRCK CICPPYRNIS GHIYNQNVSQ KDCNCLHVVE PMPVPGHDVE AYCLLCECRY EERSTTTIKV IIVIYLSVVG ALLLYMAFLM LVDPLIRKPD AYTEQLHNEE ENEDARSMAA AAASLGGPRA NTVLERVEGA QQRWKLQVQE QRKTVFDRHK MLS