TLG2_YEAST » T-SNARE affecting a late Golgi compartment protein 2

TLG2_YEAST » T-SNARE affecting a late Golgi compartment protein 2
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Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
TLG2_YEAST » T-SNARE affecting a late Golgi compartment protein 2 » Syntaxin TLG2;
Hydrophobic Thickness 31.2 ± 4.2 Å
Tilt Angle 1 ± 9°
ΔGtransfer -25.0 kcal/mol
ΔGfold -20.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 314-335 (308-336)
Pathways

SNARE interactions in vesicular transport (KEGG)

PDB none
OPM none
Complexes none
Interactions

AIM34, Complex: TLG2:AIM34

ANP1, Complex: TLG2:ANP1

ATG27, Complex: TLG2:ATG27, PubMed

BIG1, Complex: TLG2:BIG1

BOS1, Complex: TLG2:BOS1

BSC2, Complex: TLG2:YEG7:PEX32:PTH2:CWH41..., PubMed

CALX, Complex: CALX:TLG2

CSF1, Complex: TLG2:CSF1

CWH41, Complex: TLG2:YEG7:PEX32:PTH2:CWH41:MRC1:RGA2:YP035:FOLC:VPS45:ECM29:KHSE:PUR6:LAA1:DIG1:PRP5:DBF4:YD199:RPN3:OPI9:HAL5:STE12:SIR1:BSC2, PubMed

DPM1, Complex: DPM1:TLG2, PubMed

EMC1, Complex: TLG2:EMC1

EMP24, Complex: EMP24:TLG2

ERG5, Complex: TLG2:ERG5

ERP1, Complex: ERP1:TLG2

ERP2, Complex: ERP2:TLG2, PubMed

ERP4, Complex: ERP4:TLG2

ERP5, Complex: ERP5:TLG2

FAR10, Complex: TLG2:FAR10

GDA1, Complex: GDA1:TLG2

GNT1, Complex: TLG2:GNT1, PubMed

GOSR1, Complex: TLG2:GOSR1, PubMed

GPI3, Complex: TLG2:GPI3

GPI8, Complex: TLG2:GPI8

HOC1, Complex: TLG2:HOC1

KEX2, Complex: TLG2:KEX2

KRE2, Complex: TLG2:KRE2, PubMed

KTR1, Complex: TLG2:KTR1, PubMed

KTR3, Complex: TLG2:KTR3, PubMed

KTR4, Complex: TLG2:KTR4, PubMed

MMM1, Complex: TLG2:MMM1

MNN10, Complex: MNN10:TLG2

MNN11, Complex: MNN11:TLG2

MNN2, Complex: TLG2:MNN2

MSMO, Complex: TLG2:MSMO

NCB5R, Complex: TLG2:NCB5R

NEM1, Complex: TLG2:NEM1

OPI9, Complex: TLG2:YEG7:PEX32:PTH2:CWH41:MRC1:RGA2:YP035:FOLC:VPS45:ECM29:KHSE:PUR6:LAA1:DIG1:PRP5:DBF4:YD199:RPN3:OPI9:HAL5:STE12:SIR1:BSC2, PubMed

OSTB, Complex: TLG2:OSTB

PMP2, Complex: TLG2:PMP2, PubMed

PSD1, Complex: PSD1:TLG2

QCR8, Complex: QCR8:TLG2

SEC11, Complex: TLG2:SEC11

SEC22, Complex: TLG2:SEC22

SEC66, Complex: TLG2:SEC66

SED5, Complex: SED5:TLG2

SNC1, Complex: TLG2:SNC1

SNC2, Complex: TLG2:SNC2, PubMed

SOP4, Complex: TLG2:SOP4

SSO1, Complex: SSO1:TLG2, PubMed

SSO2, Complex: SSO2:TLG2

TLG1, Complex: GRP78:HSP72:SEC17:VPS45:YKT6:VTI1:TLG2:TLG1, PubMed

TMEDA, Complex: TMEDA:TLG2

UPPS, Complex: UPPS:TLG2

VPS10, Complex: VPS10:TLG2, PubMed

VPS64, Complex: TLG2:VPS64

VTI1, Complex: VTI1:TLG2, PubMed

YNS1, Complex: TLG2:YNS1

Domains

AA: 280-332, PDBID: 4XTR, Subunit G, Seq Identity:44%, SNARE domain

UniProt annotation for TLG2_YEAST » T-SNARE affecting a late Golgi compartment protein 2
FUNCTION: t-SNARE that functions in transport from the endosome to the late Golgi and on the endocytic pathway.

SUBUNIT: Interacts with VPS45.

UniProt features for TLG2_YEAST » T-SNARE affecting a late Golgi compartment protein 2
CHAIN 1 397 T-SNARE affecting a late Golgi compartment protein 2.
DOMAIN 244 306 t-SNARE coiled-coil homology.
COILED 74 96 Potential.
Amino Acid Sequence for TLG2_YEAST » T-SNARE affecting a late Golgi compartment protein 2
MFRDRTNLFL SYRRTFPHNI TFSSGKAPLG DDQDIEMGTY PMMNMSHDIS ARLTDERKNK HENHSDALPP IFIDIAQDVD DYLLEVRRLS EQLAKVYRKN SLPGFEDKSH DEALIEDLSF KVIQMLQKCY AVMKRLKTIY NSQFVDGKQL SREELIILDN LQKIYAEKIQ TESNKFRVLQ NNYLKFLNKD DLKPIRNKAS AENTLLLDDE EEEAAREKRE GLDIEDYSKR TLQRQQQLHD TSAEAYLRER DEEITQLARG VLEVSTIFRE MQDLVVDQGT IVDRIDYNLE NTVVELKSAD KELNKATHYQ KRTQKCKVIL LLTLCVIALF FFVMLKPHGG GSGGRNNGSN KYNNDDNKTV NNSHDDGSNT HINDEESNLP SIVEVTESEN DALDDLL