TIM14_DICDI » Mitochondrial import inner membrane translocase subunit TIM14

TIM14_DICDI » Mitochondrial import inner membrane translocase subunit TIM14
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Topology in Mitochondrial inner membrane
Topologyintermembrane space
mitochondrial matrix side
TIM14_DICDI » Mitochondrial import inner membrane translocase subunit TIM14 » DnaJ homolog subfamily C member 19;
Hydrophobic Thickness 27.8 ± 4.4 Å
Tilt Angle 48 ± 0°
ΔGtransfer -11.8 kcal/mol
ΔGfold -5.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 2-26 (2-30)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 62-113, PDBID: 2YS8, Subunit A, Seq Identity:34%, DnaJ domain
UniProt annotation for TIM14_DICDI » Mitochondrial import inner membrane translocase subunit TIM14
FUNCTION: Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity).

SUBUNIT: Probable component of the PAM complex at least composed of a mitochondrial HSP70 protein, grepE, tim16 and tim14.

UniProt features for TIM14_DICDI » Mitochondrial import inner membrane translocase subunit TIM14
CHAIN 1 113 Mitochondrial import inner membrane translocase subunit TIM14.
DOMAIN 59 113 J.
Amino Acid Sequence for TIM14_DICDI » Mitochondrial import inner membrane translocase subunit TIM14
MATPIIVGAT IAGIAYSSRF LIRVIQRAKS KQLFEMVSTP GFTVETIEDG FENKMTPAEA ANILGLKEES TKEEIKIRHK LLMIKNHPDK GGSSYLATKI NEARNVLSSK NSN