THY1_HUMAN » Thy-1 membrane glycoprotein

THY1_HUMAN » Thy-1 membrane glycoprotein
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
THY1_HUMAN » Thy-1 membrane glycoprotein » CDw90;Thy-1 antigen;
Hydrophobic Thickness 33.2 ± 3.4 Å
Tilt Angle 22 ± 0°
ΔGtransfer -17.6 kcal/mol
ΔGfold -8.5 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 135-159 (135-160)
Pathways

Leukocyte transendothelial migration (KEGG)

PDB none
OPM none
Complexes none
Interactions

ITAM, Complex: THY1:ITAM, PubMed

ITAV, Complex: THY1:ITAV, PubMed

ITB3, Complex: ITB3:THY1, PubMed

SCO2, Complex: THY1:SCO2

Domains

AA: 21-119, PDBID: 1B6U, Subunit A, Seq Identity:19%, Immunoglobulin domain

UniProt annotation for THY1_HUMAN » Thy-1 membrane glycoprotein
FUNCTION: May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
UniProt features for THY1_HUMAN » Thy-1 membrane glycoprotein
SIGNAL 1 19
CHAIN 20 130 Thy-1 membrane glycoprotein.
PROPEP 131 161 Removed in mature form (By similarity).
DOMAIN 20 126 Ig-like V-type.
DISULFID 28 130 By similarity.
DISULFID 38 104 By similarity.
Amino Acid Sequence for THY1_HUMAN » Thy-1 membrane glycoprotein
MNLAISIALL LTVLQVSRGQ KVTSLTACLV DQSLRLDCRH ENTSSSPIQY EFSLTRETKK HVLFGTVGVP EHTYRSRTNF TSKYNMKVLY LSAFTSKDEG TYTCALHHSG HSPPISSQNV TVLRDKLVKC EGISLLAQNT SWLLLLLLSL SLLQATDFMS L