THSD1_HUMAN » Thrombospondin type-1 domain-containing protein 1

THSD1_HUMAN » Thrombospondin type-1 domain-containing protein 1
Magnify THSD1_HUMAN » Thrombospondin type-1 domain-containing protein 1Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
THSD1_HUMAN » Thrombospondin type-1 domain-containing protein 1 » Transmembrane molecule with thrombospondin module;
Hydrophobic Thickness 33.2 ± 1.8 Å
Tilt Angle 27 ± 2°
ΔGtransfer -26.5 kcal/mol
ΔGfold -18.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 414-439 (414-439)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 344-392, PDBID: 1LSL, Subunit A, Seq Identity:39%, Thrombospondin type 1 domain

UniProt annotation for THSD1_HUMAN » Thrombospondin type-1 domain-containing protein 1
SUBCELLULAR LOCATION: Isoform 1: Membrane; Single-pass type I membrane protein (Potential).
SUBCELLULAR LOCATION: Isoform 2: Membrane; Single-pass type I membrane protein (Potential).
SUBCELLULAR LOCATION: Isoform 3: Secreted.
UniProt features for THSD1_HUMAN » Thrombospondin type-1 domain-containing protein 1
SIGNAL 1 24 Potential.
CHAIN 25 852 Thrombospondin type-1 domain-containing protein 1.
DOMAIN 340 393 TSP type-1.
DISULFID 352 387 By similarity.
DISULFID 356 392 By similarity.
DISULFID 367 377 By similarity.
Amino Acid Sequence for THSD1_HUMAN » Thrombospondin type-1 domain-containing protein 1
MKPMLKDFSN LLLVVLCDYV LGEAEYLLLR EPGHVALSND TVYVDFQYFD GANGTLRNVS VLLLEANTNQ TVTTKYLLTN QSQGTLKFEC FYFKEAGDYW FTMTPEATDN STPFPWWEKS AFLKVEWPVF HVDLNRSAKA AEGTFQVGLF TSQPLCPFPV DKPNIVVDVI FTNSLPEARR NSRQPLEIRT SKRTELAQGQ WVEFGCAPLG PEAYVTVVLK LLGRDSVITS TGPIDLAQKF GYKLVMVPEL TCESGVEVTV LPPPCTFVQG VVTVFKEAPR YPGKRTIHLA ENSLPLGERR TIFNCTLFDM GKNKYCFDFG ISSRSHFSAK EECMLIQRNT ETWGLWQPWS QCSATCGDGV RERRRVCLTS FPSSPVCPGM SLEASLCSLE ECAAFQPSSP SPLQPQGPVK SNNIVTVTGI SLCLFIIIAT VLITLWRRFG RPAKCSTPAR HNSIHSPSFR KNSDEENICE LSEQRGSFSD GGDGPTGSPG DTGIPLTYRR SGPVPPEDDA SGSESFQSNA QKIIPPLFSY RLAQQQLKEM KKKGLTETTK VYHVSQSPLT DTAIDAAPSA PLDLESPEEA AANKFRIKSP FPEQPAVSAG ERPPSRLDLN VTQASCAISP SQTLIRKSQA RHVGSRGGPS ERSHARNAHF RRTASFHEAR QARPFRERSM STLTPRQAPA YSSRTRTCEQ AEDRFRPQSR GAHLFPEKLE HFQEASGTRG PLNPLPKSYT LGQPLRKPDL GDHQAGLVAG IERTEPHRAR RGPSPSHKSV SRKQSSPISP KDNYQRVSSL SPSQCRKDKC QSFPTHPEFA FYDNTSFGLT EAEQRMLDLP GYFGSNEEDE TTSTLSVEKL VI