THE1_ARATH » Receptor-like protein kinase THESEUS 1

THE1_ARATH » Receptor-like protein kinase THESEUS 1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
THE1_ARATH » Receptor-like protein kinase THESEUS 1 »
Hydrophobic Thickness 34.4 ± 3.4 Å
Tilt Angle 30 ± 3°
ΔGtransfer -22.7 kcal/mol
ΔGfold -17.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 415-440 (410-446)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 34-387, Carbohydrate-binding protein of the ER

AA: 510-780, PDBID: 2NRU, Subunit B, Seq Identity:42%, Protein tyrosine kinase

UniProt annotation for THE1_ARATH » Receptor-like protein kinase THESEUS 1
FUNCTION: Receptor-like protein kinase required for cell elongation during vegetative growth, mostly in a brassinosteroid- (BR-) independent manner. Mediates the response of growing plant cells to the perturbation of cellulose synthesis and may act as a cell-wall-integrity sensor. Controls ectopic-lignin accumulation in cellulose-deficient mutant backgrounds.

TISSUE SPECIFICITY: Expressed in most vegetative tissues, including leaves, stems and roots, primarily in expanding cells and vascular tissue.

INDUCTION: By brassinosteroids (BR).

MISCELLANEOUS: Semidominant suppressor of the cellulose-deficient mutant procuste1-1.

MISCELLANEOUS: This protein was called "Theseus" after the Greek mythological figure Theseus, who slew the brigand Procustes.

UniProt features for THE1_ARATH » Receptor-like protein kinase THESEUS 1
SIGNAL 1 22 Potential.
CHAIN 23 855 Receptor-like protein kinase THESEUS 1.
DOMAIN 510 783 Protein kinase.
ACT_SITE 634 634 Proton acceptor (By similarity).
Amino Acid Sequence for THE1_ARATH » Receptor-like protein kinase THESEUS 1
MVFTKSLLVL LWFLSCYTTT TSSALFNPPD NYLISCGSSQ NITFQNRIFV PDSLHSSLVL KIGNSSVATS TTSNNSTNSI YQTARVFSSL ASYRFKITSL GRHWIRLHFS PINNSTWNLT SASITVVTED FVLLNNFSFN NFNGSYIFKE YTVNVTSEFL TLSFIPSNNS VVFVNAIEVV SVPDNLIPDQ ALALNPSTPF SGLSLLAFET VYRLNMGGPL LTSQNDTLGR QWDNDAEYLH VNSSVLVVTA NPSSIKYSPS VTQETAPNMV YATADTMGDA NVASPSFNVT WVLPVDPDFR YFVRVHFCDI VSQALNTLVF NLYVNDDLAL GSLDLSTLTN GLKVPYFKDF ISNGSVESSG VLTVSVGPDS QADITNATMN GLEVLKISNE AKSLSGVSSV KSLLPGGSGS KSKKKAVIIG SLVGAVTLIL LIAVCCYCCL VASRKQRSTS PQEGGNGHPW LPLPLYGLSQ TLTKSTASHK SATASCISLA STHLGRCFMF QEIMDATNKF DESSLLGVGG FGRVYKGTLE DGTKVAVKRG NPRSEQGMAE FRTEIEMLSK LRHRHLVSLI GYCDERSEMI LVYEYMANGP LRSHLYGADL PPLSWKQRLE ICIGAARGLH YLHTGASQSI IHRDVKTTNI LLDENLVAKV ADFGLSKTGP SLDQTHVSTA VKGSFGYLDP EYFRRQQLTE KSDVYSFGVV LMEVLCCRPA LNPVLPREQV NIAEWAMAWQ KKGLLDQIMD SNLTGKVNPA SLKKFGETAE KCLAEYGVDR PSMGDVLWNL EYALQLEETS SALMEPDDNS TNHIPGIPMA PMEPFDNSMS IIDRGGVNSG TGTDDDAEDA TTSAVFSQLV HPRGR