TGRD1_DICDI » Tiger protein D1

TGRD1_DICDI » Tiger protein D1
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
TGRD1_DICDI » Tiger protein D1 » Loose aggregate C2 protein;Loose aggregate D1 protein;Transmembrane, IPT, Ig, E-set, Repeat protein D1;
Hydrophobic Thickness 34.4 ± 7.4 Å
Tilt Angle 20 ± 13°
ΔGtransfer -14.6 kcal/mol
ΔGfold -9.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 866-891 (860-891)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 295-381, PDBID: 3KYA, Subunit A, Seq Identity:21%, IPT/TIG domain

AA: 556-640, PDBID: 2UZY, Subunit B, Seq Identity:18%, IPT/TIG domain

UniProt annotation for TGRD1_DICDI » Tiger protein D1
FUNCTION: May be involved in the regulation of aggregation. Activates tgrC1.

DEVELOPMENTAL STAGE: Developmentally regulated; with a peak of expression at 16 hours corresponding to the finger stage of development.

UniProt features for TGRD1_DICDI » Tiger protein D1
SIGNAL 1 21 Potential.
CHAIN 22 895 Tiger protein D1.
DOMAIN 295 381 IPT/TIG 1.
DOMAIN 560 638 IPT/TIG 2.
DOMAIN 642 725 IPT/TIG 3.
Amino Acid Sequence for TGRD1_DICDI » Tiger protein D1
MIHKMYFFLI LLFSLFIIVY SAPNRVTRNE TSIVYTYSLD SDYYTRFVMY LNATTLRTDI APNYFDCSQI VNSERYCVFH FADSFSRLWG AVYSRVCTRT VSDPTEDCQS TWITDNAFPE PLNVKFSGYP STSGGDVVFT GLFLRLAGGP NTLANSFTNP SKTFLIKVHG NFSDPNFNCN NFTATFPPSS GYIKVYFDDT GKSSLQLRYA SPTVSSFILD ESKKLVTING DNYFTKNSLV QVFFDGIIQN NINITVNHSQ IQVNNFIRVD PGPMSVNITI NAVSIDNNYT YCFPAVISSI SSVSNHLGGV VTIKGSKLSS TSIIPTIKIG DKQCTFIKST TTELECQLEP NETGGKHLPV DVNFGGCNST SSGSDAVTFT YSIPTLSSGT LSNGIVTLIG TNLGTINDSF IQLNSNGAID NVKNDQFNIS SDETTATFKL PLLKCKSFYI NFTRVDISAN NKPSISAPLL IYVINKPTVS NGSINIELYY IDCPISPSST PSITVGNSSS ATQCSIPSLK NLSEYYQTTC SIPYGTGTNK QFKFKYNSEE SNSEFSYEPP KVESRSFSKG LFNITINGNN FGNSTSLIKV YFNGSDISSE IQSLNDNQFT FKRLNSYENG PINITVDGNS NMEPSFYLTL PPVIYSIINK ENKTIGCGGL ITISGKNLLT SDDKFKVRVL ANNENTTVIV PDEKTLIVRA NNKDSPLFVS TLIGDDLGPN TTLTYFEPRI TVIPTVKNKK DGISIRVGGV SLSGIINASL GISSENVSLS CDLQCSLSPN ETFYLSNPIL SSNEKDITNS TDCLSCHSMN SIVVDETSGV LYLQLGPTSY HYDVKIEEIQ SSLNPSSSNG GERKSSKLSG GAIAGITIGC VAGAGALVGS VFYFKLITRV KKAFN