TATA_ARATH » Sec-independent protein translocase protein TATA, chloroplastic

TATA_ARATH » Sec-independent protein translocase protein TATA, chloroplastic
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Topology in Thylakoid membrane
Topologythylakoid lumen
chloroplast stroma
TATA_ARATH » Sec-independent protein translocase protein TATA, chloroplastic » Protein THYLAKOID ASSEMBLY 4;Protein TWIN-ARGININE TRANSLOCATION A;
Hydrophobic Thickness 34.0 ± 4.0 Å
Tilt Angle 7 ± 8°
ΔGtransfer -21.2 kcal/mol
ΔGfold -5.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 63-87 (60-87)
Pathways none
PDB none
OPM 2lzr (ECOLI), 2lzs (ECOLI)
Complexes

TATA:TATA_ECOLI

Interactions none
Domains

AA: 66-141, PDBID: 2L16, Subunit A, Seq Identity:29%, mttA/Hcf106 family

UniProt annotation for TATA_ARATH » Sec-independent protein translocase protein TATA, chloroplastic
FUNCTION: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation (By similarity).

SUBUNIT: In thylakoid membranes, TATC and TATB form a large receptor complex, containing about eight TATC-TATB pairs, which binds the precursor protein. Twin arginine signal peptide promotes pH-triggered docking of TATA oligomers to TATC-TATB receptor complex, inducing a conformational switch of TATA that results in activation of the translocase. TATA dissociates from TATC-TATB upon completion of translocation.

UniProt features for TATA_ARATH » Sec-independent protein translocase protein TATA, chloroplastic
TRANSIT 1 59 Chloroplast (Potential).
CHAIN 60 147 Sec-independent protein translocase protein TATA, chloroplastic.
Amino Acid Sequence for TATA_ARATH » Sec-independent protein translocase protein TATA, chloroplastic
MATSVATLSS PPPVSLPLLS SSRSSFFSNC FTVTTRPNTR SLVAIGRRIR QEPTRKPLTC NALFGLGVPE LAVIAGVAAL LFGPKKLPEI GKSIGKTVKS FQQAAKEFES ELKTEPEESV AESSQVATSN KEEEKKTEVS SSSKENV