SYT2_ARATH » Synaptotagmin-2

SYT2_ARATH » Synaptotagmin-2
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Topology in Golgi apparatus membrane
TopologyGolgi lumenal side
cytoplasmic side
SYT2_ARATH » Synaptotagmin-2 » NTMC2T1.2;Synaptotagmin B;
Hydrophobic Thickness 36.8 ± 1.8 Å
Tilt Angle 0 ± 7°
ΔGtransfer -40.7 kcal/mol
ΔGfold -14.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 3-31 (3-34)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 67-249, PDBID: 4P42, Subunit B, Seq Identity:27%, Synaptotagmin-like mitochondrial-lipid-binding domain

AA: 260-364, PDBID: 2NSQ, Subunit A, Seq Identity:36%, C2 domain

AA: 418-519, PDBID: 2DMG, Subunit A, Seq Identity:26%, C2 domain

UniProt annotation for SYT2_ARATH » Synaptotagmin-2
FUNCTION: May play an important role in regulating an unconventional protein trafficking from the cytosol to the extracelluar matrix.
UniProt features for SYT2_ARATH » Synaptotagmin-2
CHAIN 1 537 Synaptotagmin-2.
DOMAIN 247 346 C2 1.
DOMAIN 405 501 C2 2.
REGION 227 505 Phospholipid binding (By similarity).
Amino Acid Sequence for SYT2_ARATH » Synaptotagmin-2
MGIISTILGV IGFGFGTTIG IVIGYYLFIY FQSTDVEDPE IKPLVELDSE TIATMFPEIP MWVKNPDFDR IDWLNKLIGH MWPYMDKAIC KMAKSIAKPI IAEQIPNYKI DSVEFEMLTL GSLPPSFQGM KVYATDDKEI IMELSVKWAG NPNIIVVAKA FGLKATVQVI DLQVYATPRI TLKPLVPSFP CFANIFVSLM DKPQVDFGLK LLGADVMAIP GLYRFVQEII KDQVANMYLW PKTLNVQIMD PSKAMKKPVG LLSVKVIKAI KLKKKDLLGG SDPYVKLTLS GDKVPGKKTV VKHSNLNPEW NEEFDLVVKE PESQELQLIV YDWEQVGKHD KIGMNVIQLK DLTPEEPKLM TLELLKSMEP KEPVSEKSRG QLVVEVEYKP FKDDDIPENI DDPNAVEKAP EGTPSTGGLL VVIVHEAEDL EGKYHTNPSV RLLFRGEERK TKRVKKNREP RWDEDFQFPL DEPPINDKLH VEVISSSSRL IHPKETLGYV VINLGDVVSN RRINDKYHLI DSKNGRIQIE LQWRNSS