SYP22_ARATH » Syntaxin-22

SYP22_ARATH » Syntaxin-22
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Topology in Vacuolar membrane
Topologyvacuole lumenal side
cytoplasmic side
SYP22_ARATH » Syntaxin-22 » AtSYP22; AtVAM3;
Hydrophobic Thickness 34.0 ± 1.9 Å
Tilt Angle 4 ± 4°
ΔGtransfer -29.6 kcal/mol
ΔGfold -24.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 246-268 (244-268)
Pathways none
PDB none
OPM none
Complexes none
Interactions

SYP21, Complex: SYP21:SYP22

SYP51, Complex: SYP22:SYP51

SYP52, Complex: SYP22:SYP52

SYP71, Complex: SYP71:SYP22, PubMed

VA711, Complex: SYP22:VA711, PubMed

VA713, Complex: SYP22:VA713, PubMed

VA714, Complex: SYP22:VA714, PubMed

VA721, Complex: SYP22:VA721, PubMed

VTI11, Complex: VTI11:SYP22, PubMed

VTI12, Complex: SYP22:VTI12

Domains

AA: 28-129, PDBID: 2DNX, Subunit A, Seq Identity:27%, Syntaxin-like protein

AA: 211-263, PDBID: 2XHE, Subunit B, Seq Identity:30%, SNARE domain

UniProt annotation for SYP22_ARATH » Syntaxin-22
FUNCTION: May provide the t-SNARE function in the vacuolar assembly. Promotes the formation of vacuolar membrane "bulbs". Required for inflorescence stem gravitropism.

SUBUNIT: Interacts with VTI11 and SYP51 to form a t-SNARE complex, but not with VPS45.

TISSUE SPECIFICITY: Expressed in roots, leaves, stems, flower and green siliques.

UniProt features for SYP22_ARATH » Syntaxin-22
CHAIN 1 268 Syntaxin-22.
DOMAIN 175 237 t-SNARE coiled-coil homology.
Amino Acid Sequence for SYP22_ARATH » Syntaxin-22
MSFQDLESGR GRSTRKFNGG RQDSTQAVAS GIFQINTGVS TFQRLVNTLG TPKDTPELRE KLHKTRLHIG QLVKDTSAKL KEASETDHQS GVNPSKKIAD AKLARDFQAV LKEFQKAQQT AAERETTYTP FVPQSALPSS YTAGEVDKVP EQRAQLQESK RQELVLLDNE IAFNEAVIEE REQGIQEIHQ QIGEVNEIFK DLAVLVNDQG VMIDDIGTHI DNSRAATSQG KSQLVQAAKT QKSNSSLTCL LLVIFGIVLL IVIIVLAA