SYP21_ARATH » Syntaxin-21

SYP21_ARATH » Syntaxin-21
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Topology in Endosome membrane
Topologyendosome lumenal side
cytoplasmic side
SYP21_ARATH » Syntaxin-21 » AtSYP21; PEP12 homolog;AtPEP12; aPEP12;
Hydrophobic Thickness 30.4 ± 1.8 Å
Tilt Angle 0 ± 0°
ΔGtransfer -44.6 kcal/mol
ΔGfold -23.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 257-278 (255-278)
Pathways

Phagosome (KEGG)

SNARE interactions in vesicular transport (KEGG)

PDB none
OPM none
Complexes none
Interactions

NPS11, Complex: SYP21:NPS11, PubMed

SSRA, Complex: SSRA:SYP21, PubMed

SYP22, Complex: SYP21:SYP22

SYP51, Complex: SYP21:SYP51

SYP52, Complex: SYP21:SYP52

SYP61, Complex: SYP21:SYP61, PubMed

VA711, Complex: SYP21:VA711, PubMed

VSR1, Complex: SYP21:VSR1

VTI11, Complex: SYP21:VTI11

Domains

AA: 36-137, PDBID: 2DNX, Subunit A, Seq Identity:31%, Syntaxin-like protein

AA: 222-274, PDBID: 2XHE, Subunit B, Seq Identity:30%, SNARE domain

UniProt annotation for SYP21_ARATH » Syntaxin-21
FUNCTION: May function in the docking or fusion of transport vesicles with the prevacuolar membrane.

SUBUNIT: Interacts with VTI11 and SYP51 to form a t-SNARE complex and with alpha-SNAP to form a 20S complex.

TISSUE SPECIFICITY: A high level expression is seen in the roots while a low level expression is seen in the leaves.

UniProt features for SYP21_ARATH » Syntaxin-21
CHAIN 1 279 Syntaxin-21.
DOMAIN 186 248 t-SNARE coiled-coil homology.
COILED 65 94 Potential.
Amino Acid Sequence for SYP21_ARATH » Syntaxin-21
MSFQDLEAGT RSPAPNRFTG GRQQRPSSRG DPSQEVAAGI FRISTAVNSF FRLVNSIGTP KDTLELRDKL QKTRLQISEL VKNTSAKLKE ASEADLHGSA SQIKKIADAK LAKDFQSVLK EFQKAQRLAA EREITYTPVV TKEIPTSYNA PELDTESLRI SQQQALLLQS RRQEVVFLDN EITFNEAIIE EREQGIREIE DQIRDVNGMF KDLALMVNHQ GNIVDDISSN LDNSHAATTQ ATVQLRKAAK TQRSNSSLTC LLILIFGIVL LIVIIVVLV