SYJ2B_HUMAN » Synaptojanin-2-binding protein

SYJ2B_HUMAN » Synaptojanin-2-binding protein
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Topology in Mitochondrial outer membrane
Topologyintermembrane space
cytoplasmic side
SYJ2B_HUMAN » Synaptojanin-2-binding protein » Mitochondrial outer membrane protein 25;
Hydrophobic Thickness 30.8 ± 2.4 Å
Tilt Angle 28 ± 1°
ΔGtransfer -27.4 kcal/mol
ΔGfold -19.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 118-139 (118-144)
Pathways none
PDB 2eno (1-107), 2jin (4-99), 2jik (6-100)
OPM none
Complexes none
Interactions

A4, Complex: A4:SYJ2B, PubMed

AVR2A, Complex: RBP1:REPS2:SYJ2B:AVR2A, PubMed

AVR2A, Complex: SYJ2B:AVR2A, PubMed

AVR2B, Complex: SYJ2B:AVR2B, PubMed

DAF, Complex: SYJ2B:DAF, PubMed

ESYT1, Complex: SYJ2B:ESYT1

LRP1, Complex: SYJ2B:LRP1, PubMed

LRP2, Complex: SYJ2B:LRP2, PubMed

LRP8, Complex: SYJ2B:LRP8, PubMed

MGT4B, Complex: MGT4B:SYJ2B, PubMed

SE1L1, Complex: SYJ2B:SE1L1, PubMed

Domains

AA: 13-97, PDBID: 2ENO, Subunit A, Seq Identity:100%, PDZ domain (Also known as DHR or GLGF)

UniProt annotation for SYJ2B_HUMAN » Synaptojanin-2-binding protein
SUBUNIT: Binds (via the PDZ domain) to isoform 2A of SYNJ2 (via the unique motif in the C-terminus). Interacts with MAPK12.
UniProt features for SYJ2B_HUMAN » Synaptojanin-2-binding protein
CHAIN 1 145 Synaptojanin-2-binding protein.
DOMAIN 13 100 PDZ.
Amino Acid Sequence for SYJ2B_HUMAN » Synaptojanin-2-binding protein
MNGRVDYLVT EEEINLTRGP SGLGFNIVGG TDQQYVSNDS GIYVSRIKEN GAAALDGRLQ EGDKILSVNG QDLKNLLHQD AVDLFRNAGY AVSLRVQHRL QVQNGPIGHR GEGDPSGIPI FMVLVPVFAL TMVAAWAFMR YRQQL