SUN1_ARATH » Protein SAD1/UNC-84 domain protein 1

SUN1_ARATH » Protein SAD1/UNC-84 domain protein 1
Magnify SUN1_ARATH » Protein SAD1/UNC-84 domain protein 1Enlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Nuclear inner membrane
Topologyintermembrane space
nucleus matrix side
SUN1_ARATH » Protein SAD1/UNC-84 domain protein 1 »
Hydrophobic Thickness 29.2 ± 1.4 Å
Tilt Angle 41 ± 1°
ΔGtransfer -21.4 kcal/mol
ΔGfold -11.3 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 110-132 (100-135)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 313-451, PDBID: 3UNP, Subunit A, Seq Identity:36%, Sad1 / UNC-like C-terminal

UniProt annotation for SUN1_ARATH » Protein SAD1/UNC-84 domain protein 1
FUNCTION: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments (PubMed:24667841). Required for the maintenance and/or formation of polarized nuclear shape in root hairs (PubMed:21294795). Modulates the anchoring and mobility of WIP proteins and RANGAP1 in the nuclear envelope (NE) (PubMed:22270916).
UniProt features for SUN1_ARATH » Protein SAD1/UNC-84 domain protein 1
CHAIN 1 471 Protein SAD1/UNC-84 domain protein 1.

DOMAIN 288 452 SUN.

COILED 175 225

MOTIF 88 95 Nuclear localization signal.

Amino Acid Sequence for SUN1_ARATH » Protein SAD1/UNC-84 domain protein 1
MSASTVSITA NTAAATRRTP ILAGEKKSNF DYPQSESLAN GGVGEAGGTS RDLSRGEATL DRSQGQDLGP VTRRSVSAAT GTNTTATQRR TRKVATPKSE KARWKTVVRI FAKQLGALLI IVGLIQLTRK MILKASSPSS PISSYETEMA FSGLESRIAE VDGLVKATTN SMQVQVELLD KKMEREAKVL RQEIERKASA FQSELKKIES RTESLEKSVD EVNAKPWVTK DELERIYEEL KKGNVDDSAF SEISIDELRA YARDIMEKEI EKHAADGLGR VDYALASGGA FVMEHSDPYL VGKGSSWFAT TMRRAHTNAV KMLSPSFGEP GQCFPLKGSE GYVQIRLRGP IIPEAFTLEH VAKSVAYDRS SAPKDCRVSG SLQGPESSAE TENMQLLTEF TYDLDRSNAQ TFNILESSSS GLIDTVRLDF TSNHGSDSHT CIYRFRVHGR APDPVPVVGT NLDQDSSPES E