STX10_HUMAN » Syntaxin-10

STX10_HUMAN » Syntaxin-10
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Topology in Golgi apparatus membrane
TopologyGolgi lumenal side
cytoplasmic side
STX10_HUMAN » Syntaxin-10 » Syn10;
Hydrophobic Thickness 34.8 ± 2.6 Å
Tilt Angle 3 ± 2°
ΔGtransfer -26.1 kcal/mol
ΔGfold -21.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology In
TM Segments 227-249 (224-249)
Pathways

Neuronal System (Reactome)

SNARE interactions in vesicular transport (KEGG)

PDB 4dnd (1-108)
OPM none
Complexes none
Interactions none
Domains

AA: 5-103, PDBID: 4DND, Subunit A, Seq Identity:100%, Syntaxin 6, N-terminal

AA: 193-245, PDBID: 2NPS, Subunit D, Seq Identity:70%, SNARE domain

UniProt annotation for STX10_HUMAN » Syntaxin-10
FUNCTION: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network.

SUBUNIT: Interacts with VPS52.

TISSUE SPECIFICITY: Expressed at high levels in heart, skeletal muscle and pancreas.

UniProt features for STX10_HUMAN » Syntaxin-10
CHAIN 1 249 Syntaxin-10.
DOMAIN 157 219 t-SNARE coiled-coil homology.
COILED 41 69 Potential.
Amino Acid Sequence for STX10_HUMAN » Syntaxin-10
MSLEDPFFVV RGEVQKAVNT ARGLYQRWCE LLQESAAVGR EELDWTTNEL RNGLRSIEWD LEDLEETIGI VEANPGKFKL PAGDLQERKV FVERMREAVQ EMKDHMVSPT AVAFLERNNR EILAGKPAAQ KSPSDLLDAS AVSATSRYIE EQQATQQLIM DEQDQQLEMV SGSIQVLKHM SGRVGEELDE QGIMLDAFAQ EMDHTQSRMD GVLRKLAKVS HMTSDRRQWC AIAVLVGVLL LVLILLFSL