SRPRB_DICDI » Signal recognition particle receptor subunit beta

SRPRB_DICDI » Signal recognition particle receptor subunit beta
Magnify SRPRB_DICDI » Signal recognition particle receptor subunit betaEnlarged view of image
3D view in GLMol or JMol

gray dot

Download Coordinates

gray dot

Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
SRPRB_DICDI » Signal recognition particle receptor subunit beta » SR-beta;
Hydrophobic Thickness 32.4 ± 2.4 Å
Tilt Angle 7 ± 2°
ΔGtransfer -24.0 kcal/mol
ΔGfold -17.0 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 43-64 (43-65)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 83-261, PDBID: 1NRJ, Subunit B, Seq Identity:25%, Signal recognition particle receptor beta subunit

UniProt annotation for SRPRB_DICDI » Signal recognition particle receptor subunit beta
FUNCTION: Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR (By similarity).

SUBUNIT: Heterodimer of an alpha and a beta chain.

UniProt features for SRPRB_DICDI » Signal recognition particle receptor subunit beta
CHAIN 1 290 Signal recognition particle receptor subunit beta.
Amino Acid Sequence for SRPRB_DICDI » Signal recognition particle receptor subunit beta
MKDSAILNQL KVVLPPHIME IIYFRYNQID TYLKPYNLPI KTDVLLLALF TLIFIIIISK LFGSSGNKTR SVGGRTSNDK KVKRGVNIAI LGLSNAGKTA LLLNLTNVDK KISTHTSITT NNGVYITENK KKLPIIDVPG NGKAKASLPK ILSNSACIIY VIDGTTFIDN STQEAQYLYD ILTNESVYQK KIPVLVFNNK MDLDSTIDTE QVKNILEREL DDLRRTRGAT PIVLGQEEDK KDIYLGIEGT PFQFDHLPND VQFSNGSASP SNGELKEIDD IKNFIQTTTL