SRPB_YEAST » Signal recognition particle receptor subunit beta

SRPB_YEAST » Signal recognition particle receptor subunit beta
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
SRPB_YEAST » Signal recognition particle receptor subunit beta » SR-beta;
Hydrophobic Thickness 30.4 ± 1.2 Å
Tilt Angle 0 ± 2°
ΔGtransfer -31.2 kcal/mol
ΔGfold -16.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 5-26 (4-28)
Pathways

Protein export (KEGG)

PDB 2ged (A/B=36-183), 1nrj (B=31-244)
OPM 1nrj
Complexes

SRPB:SRPB_YEAST

Interactions

EMP24, Complex: SRPB:EMP24, PubMed

EMP47, Complex: SRPB:EMP47, PubMed

FET3, Complex: SRPB:FET3, PubMed

GPI8, Complex: SRPB:GPI8, PubMed

MMM1, Complex: SRPB:MMM1

MSMO, Complex: SRPB:MSMO, PubMed

PMP2, Complex: SRPB:PMP2, PubMed

SAC1, Complex: SRPB:SAC1, PubMed

SC6B2, Complex: SRPB:SC6B2

SRPB, Complex: Homodimer of signal recognition particle receptor subunit beta, PDBID: 2GED

Domains

AA: 36-221, PDBID: 1NRJ, Subunit B, Seq Identity:100%, Signal recognition particle receptor beta subunit

UniProt annotation for SRPB_YEAST » Signal recognition particle receptor subunit beta
FUNCTION: Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Has GTPase activity. May mediate the membrane association of SRPR.

SUBUNIT: Heterodimer of an alpha and a beta chain.

MISCELLANEOUS: Present with 8250 molecules/cell in log phase SD medium.

UniProt features for SRPB_YEAST » Signal recognition particle receptor subunit beta
CHAIN 1 244 Signal recognition particle receptor subunit beta.
Amino Acid Sequence for SRPB_YEAST » Signal recognition particle receptor subunit beta
MLSNTLIIAC LLVIGTTIAL IAVQKASSKT GIKQKSYQPS IIIAGPQNSG KTSLLTLLTT DSVRPTVVSQ EPLSAADYDG SGVTLVDFPG HVKLRYKLSD YLKTRAKFVK GLIFMVDSTV DPKKLTTTAE FLVDILSITE SSCENGIDIL IACNKSELFT ARPPSKIKDA LESEIQKVIE RRKKSLNEVE RKINEEDYAE NTLDVLQSTD GFKFANLEAS VVAFEGSINK RKISQWREWI DEKL