SRF8_ARATH » Protein STRUBBELIG-RECEPTOR FAMILY 8

SRF8_ARATH » Protein STRUBBELIG-RECEPTOR FAMILY 8
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
SRF8_ARATH » Protein STRUBBELIG-RECEPTOR FAMILY 8 » Leucine-rich repeat receptor kinase-like protein SRF8;
Hydrophobic Thickness 29.6 ± 2.4 Å
Tilt Angle 0 ± 0°
ΔGtransfer -38.3 kcal/mol
ΔGfold -18.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 289-313 (289-317)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BETL2, Complex: SRF8:BETL2

CRK40, Complex: SRF8:CRK40

MSBP2, Complex: SRF8:MSBP2

PAM74, Complex: SRF8:PAM74

UBC34, Complex: SRF8:UBC34

VAP21, Complex: SRF8:VAP21

WAK3, Complex: SRF8:WAK3

Domains

AA: 30-71, PDBID: 4M7E, Subunit D, Seq Identity:30%, Leucine rich repeat N-terminal domain

AA: 119-179, PDBID: 4MN8, Subunit A, Seq Identity:38%, Leucine rich repeat

AA: 395-669, PDBID: 4YFF, Subunit A, Seq Identity:38%, Protein tyrosine kinase

UniProt annotation for SRF8_ARATH » Protein STRUBBELIG-RECEPTOR FAMILY 8
TISSUE SPECIFICITY: Expressed in seedlings, roots, stems, leaves, flowers and siliques.

DOMAIN: The protein kinase domain is predicted to be catalytically inactive.

MISCELLANEOUS: Cannot functionally replace STRUBBELIG.

MISCELLANEOUS: Over-expression of SRF8 may lead to seedling lethality in both cv. Landsberg and cv. Columbia.

UniProt features for SRF8_ARATH » Protein STRUBBELIG-RECEPTOR FAMILY 8
SIGNAL 1 27 Potential.
CHAIN 28 703 Protein STRUBBELIG-RECEPTOR FAMILY 8.
REPEAT 96 120 LRR 1.
REPEAT 122 142 LRR 2.
REPEAT 143 165 LRR 3.
REPEAT 166 190 LRR 4.
REPEAT 192 212 LRR 5.
REPEAT 213 233 LRR 6.
REPEAT 234 256 LRR 7.
DOMAIN 395 672 Protein kinase.
Amino Acid Sequence for SRF8_ARATH » Protein STRUBBELIG-RECEPTOR FAMILY 8
MAIGDRAMFT VLLLFIASIS GFSVVRCVTD PSDVQALQVL YTSLNSPSQL TNWKNGGGDP CGESWKGITC EGSAVVTIDI SDLGVSGTLG YLLSDLKSLR KLDVSGNSIH DTLPYQLPPN LTSLNLARNN LSGNLPYSIS AMGSLSYMNV SGNSLTMSIG DIFADHKSLA TLDLSHNNFS GDLPSSLSTV STLSVLYVQN NQLTGSIDVL SGLPLKTLNV ANNHFNGSIP KELSSIQTLI YDGNSFDNVP ASPQPERPGK KETPSGSKKP KIGSEEKSSD SGKGLSGGVV TGIVFGSLFV AGIIALVLYL CLHKKKRKVR GSTRASQRSL PLSGTPEVQE QRVKSVASVA DLKSSPAEKV TVDRVMKNGS ISRIRSPITA SQYTVSSLQV ATNSFSQENI IGEGSLGRVY RAEFPNGKIM AIKKIDNAAL SLQEEDNFLE AVSNMSRLRH PNIVPLAGYC TEHGQRLLVY EYVGNGNLDD TLHTNDDRSM NLTWNARVKV ALGTAKALEY LHEVCLPSIV HRNFKSANIL LDEELNPHLS DSGLAALTPN TERQVSTQVV GSFGYSAPEF ALSGIYTVKS DVYTFGVVML ELLTGRKPLD SSRTRAEQSL VRWATPQLHD IDALSKMVDP SLNGMYPAKS LSRFADIIAL CIQPEPEFRP PMSEVVQQLV RLVQRASVVK RRSSDDTGFS YRTPEHEHVD ISF