SNC2_YEAST » Synaptobrevin homolog 2

SNC2_YEAST » Synaptobrevin homolog 2
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Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
SNC2_YEAST » Synaptobrevin homolog 2 »
Hydrophobic Thickness 34.0 ± 2.6 Å
Tilt Angle 24 ± 3°
ΔGtransfer -32.8 kcal/mol
ΔGfold -24.6 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 89-114 (86-114)
Pathways

SNARE interactions in vesicular transport (KEGG)

PDB none
OPM none
Complexes none
Interactions

BET1, Complex: SNC2:BET1, PubMed

BOS1, Complex: SNC2:BOS1, PubMed

GDA1, Complex: GDA1:SNC2

HOC1, Complex: SNC2:HOC1

MNN11, Complex: MNN11:SNC2

OSTB, Complex: SNC2:OSTB

PEP12, Complex: PEP12:SNC2

SEC22, Complex: SEC22:SNC2, PubMed

SEC66, Complex: SNC2:SEC66

SED5, Complex: SED5:SNC2, PubMed

SFT1, Complex: SFT1:SNC2

SNC1, Complex: SNC1:SNC2

SSO1, Complex: SSO1:SEC9:SNC2, PubMed

SSO2, Complex: SSO2:SNC2, PubMed

TLG1, Complex: TLG1:SNC2, PubMed

TLG2, Complex: TLG2:SNC2, PubMed

VAM3, Complex: VAM3:SNC2

VTI1, Complex: VTI1:SNC2, PubMed

Domains

AA: 24-112, PDBID: 3B5N, Subunit A, Seq Identity:83%, Synaptobrevin

UniProt annotation for SNC2_YEAST » Synaptobrevin homolog 2
FUNCTION: SNC1 and SNC2 are vesicle-targeting proteins essential for normal secretory traffic between the Golgi and the plasma membrane. They may also be involved in vesicle fusion.

MISCELLANEOUS: Present with 300 molecules/cell in log phase SD medium.

UniProt features for SNC2_YEAST » Synaptobrevin homolog 2
CHAIN 1 115 Synaptobrevin homolog 2.
DOMAIN 27 87 v-SNARE coiled-coil homology.
CROSSLNK 62 62 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin).
Amino Acid Sequence for SNC2_YEAST » Synaptobrevin homolog 2
MSSSVPYDPY VPPEESNSGA NPNSQNKTAA LRQEIDDTVG IMRDNINKVA ERGERLTSIE DKADNLAISA QGFKRGANRV RKQMWWKDLK MRMCLFLVVI ILLVVIIVPI VVHFS