SNC1_YEAST » Synaptobrevin homolog 1

SNC1_YEAST » Synaptobrevin homolog 1
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Topology in Vesicle membrane
Topologyvesicle lumenal side
cytoplasmic side
SNC1_YEAST » Synaptobrevin homolog 1 »
Hydrophobic Thickness 38.8 ± 5.0 Å
Tilt Angle 6 ± 2°
ΔGtransfer -32.9 kcal/mol
ΔGfold -27.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology In
TM Segments 90-116 (87-116)
Pathways

SNARE interactions in vesicular transport (KEGG)

PDB 3b5n (A/E/I=27-86)
OPM none
Complexes

SNC1:SSO1:SEC9_YEAST

Interactions

ERG2, Complex: ERG2:SNC1

PEP12, Complex: PEP12:SNC1, PubMed

PEP12, Complex: YKT6:VTI1:PEP12:STX8:SNC1, PubMed

SNC2, Complex: SNC1:SNC2

SSO1, Complex: SSO1:SNC1, PDBID: 3B5N, PubMed

SSO2, Complex: SSO2:SNC1, PubMed

STX8, Complex: STX8:SNC1, PubMed

TLG1, Complex: TLG1:SNC1, PubMed

TLG2, Complex: TLG2:SNC1

VAM3, Complex: VAM3:SNC1

Domains

AA: 25-113, PDBID: 3B5N, Subunit A, Seq Identity:100%, Synaptobrevin

UniProt annotation for SNC1_YEAST » Synaptobrevin homolog 1
FUNCTION: SNC1 and SNC2 are vesicle-targeting proteins essential for normal secretory traffic between the Golgi and the plasma membrane. They may also be involved in vesicle fusion.
UniProt features for SNC1_YEAST » Synaptobrevin homolog 1
CHAIN 1 117 Synaptobrevin homolog 1.
DOMAIN 28 88 v-SNARE coiled-coil homology.
CROSSLNK 63 63 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin).
Amino Acid Sequence for SNC1_YEAST » Synaptobrevin homolog 1
MSSSTPFDPY ALSEHDEERP QNVQSKSRTA ELQAEIDDTV GIMRDNINKV AERGERLTSI EDKADNLAVS AQGFKRGANR VRKAMWYKDL KMKMCLALVI IILLVVIIVP IAVHFSR