SLP1_YEAST » Uncharacterized protein SLP1

SLP1_YEAST » Uncharacterized protein SLP1
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
SLP1_YEAST » Uncharacterized protein SLP1 » SUN-like protein 1;
Hydrophobic Thickness 28.8 ± 3.6 Å
Tilt Angle 30 ± 0°
ΔGtransfer -18.5 kcal/mol
ΔGfold -10.4 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 538-560 (538-561)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BIG1, Complex: BIG1:SLP1

CALX, Complex: CALX:SLP1

FAR10, Complex: SLP1:FAR10

HLJ1, Complex: HLJ1:SLP1

IRE1, Complex: IRE1:SLP1

MPS3, Complex: SLP1:MPS3

OSTB, Complex: OSTB:SLP1

SEC66, Complex: SLP1:SEC66

Domains

AA: 203-330, PDBID: 3UNP, Subunit A, Seq Identity:20%, Sad1 / UNC-like C-terminal

UniProt annotation for SLP1_YEAST » Uncharacterized protein SLP1
FUNCTION: May be involved in membrane protein folding (PubMed). Required for localization of MPS3 to the nuclear envelope (PubMed).

SUBUNIT: Interacts with EMP65.

MISCELLANEOUS: Present with 3250 molecules/cell in log phase SD medium.

UniProt features for SLP1_YEAST » Uncharacterized protein SLP1
SIGNAL 1 21 Potential.
CHAIN 22 587 Uncharacterized protein SLP1.
DOMAIN 163 331 SUN.
Amino Acid Sequence for SLP1_YEAST » Uncharacterized protein SLP1
MANRLLIYGL ILWVSIIGSF ALDRNKTAQN AKIGLHDTTV ITTGSTTNVQ KEHSSPLSTG SLRTHDFRQA SKVDIRQADI RENGERKEQD ALTQPATPRN PGDSSNSFLS FDEWKKVKSK EHSSGPERHL SRVREPVDPS CYKEKECIGE ELEIDLGFLT NKNEWSEREE NQKGFNEEKD IEKVYKKKFN YASLDCAATI VKSNPEAIGA TSTLIESKDK YLLNPCSAPQ QFIVIELCED ILVEEIEIAN YEFFSSTFKR FRVSVSDRIP MVKNEWTILG EFEARNSREL QKFQIHNPQI WASYLKIEIL SHYEDEFYCP ISLIKVYGKS MMDEFKIDQL KAQEDKEQSI GTNNINNLNE QNIQDRCNNI ETRLETPNTS NLSDLAGALS CTSKLIPLKF DEFFKVLNAS FCPSKQMISS SSSSAVPVIP EESIFKNIMK RLSQLETNSS LTVSYIEEQS KLLSKSFEQL EMAHEAKFSH LVTIFNETMM SNLDLLNNFA NQLKDQSLRI LEEQKLENDK FTNRHLLHLE RLEKEVSFQR RIVYASFFAF VGLISYLLIT RELYFEDFEE SKNGAIEKAD IVQQAIR