SLAF9_HUMAN » SLAM family member 9

SLAF9_HUMAN » SLAM family member 9
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
SLAF9_HUMAN » SLAM family member 9 » CD2 family member 10;CD2F-10; CD84 homolog 1;CD84-H1;
Hydrophobic Thickness 40.0 ± 1.8 Å
Tilt Angle 0 ± 0°
ΔGtransfer -52.3 kcal/mol
ΔGfold -22.8 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 233-258 (230-263)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 17-127, PDBID: 2if7, Subunit B, Seq Identity:37%, Immunoglobulin V-set domain

AA: 135-204, Immunoglobulin domain

UniProt annotation for SLAF9_HUMAN » SLAM family member 9
FUNCTION: May play a role in the immune response.

TISSUE SPECIFICITY: Expression is predominantly restricted in hematopoietic tissues. Expressed in heart, spleen, liver, intestine, muscle and testis. Expressed in immune cells, including monocytes, dendritic, B- and T-cells. No expression was seen in peripheral blood leukocytes. Expressed in the leukocyte cell line THP-1.

UniProt features for SLAF9_HUMAN » SLAM family member 9
SIGNAL 1 18 Potential.
CHAIN 19 289 SLAM family member 9.
DOMAIN 136 210 Ig-like C2-type.
DISULFID 156 200 By similarity.
Amino Acid Sequence for SLAF9_HUMAN » SLAM family member 9
MCAFPWLLLL LLLQEGSQRR LWRWCGSEEV VAVLQESISL PLEIPPDEEV ENIIWSSHKS LATVVPGKEG HPATIMVTNP HYQGQVSFLD PSYSLHISNL SWEDSGLYQA QVNLRTSQIS TMQQYNLCVY RWLSEPQITV NFESSGEGAC SMSLVCSVEK AGMDMTYSWL SRGDSTYTFH EGPVLSTSWR PGDSALSYTC RANNPISNVS SCPIPDGPFY ADPNYASEKP STAFCLLAKG LLIFLLLVIL AMGLWVIRVQ KRHKMPRMKK LMRNRMKLRK EAKPGSSPA