SIRK_ARATH » Senescence-induced receptor-like serine/threonine-protein kinase

SIRK_ARATH » Senescence-induced receptor-like serine/threonine-protein kinase
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
SIRK_ARATH » Senescence-induced receptor-like serine/threonine-protein kinase » FLG22-induced receptor-like kinase 1;
Hydrophobic Thickness 34.8 ± 2.6 Å
Tilt Angle 18 ± 0°
ΔGtransfer -25.6 kcal/mol
ΔGfold -19.7 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING
Topology Out
TM Segments 517-541 (517-544)
Pathways none
PDB none
OPM none
Complexes none
Interactions

BET12, Complex: SIRK:BET12

TCMO, Complex: SIRK:TCMO

UBC32, Complex: SIRK:UBC32

UBC34, Complex: SIRK:UBC34

Domains

AA: 33-359, Carbohydrate-binding protein of the ER

AA: 414-474, PDBID: 4MN8, Subunit A, Seq Identity:46%, Leucine rich repeat

AA: 574-842, PDBID: 3TL8, Subunit A, Seq Identity:45%, Protein kinase domain

UniProt annotation for SIRK_ARATH » Senescence-induced receptor-like serine/threonine-protein kinase
FUNCTION: Involved in innate immune response of plants.

INDUCTION: Highly induced by WRKY22 or WRKY29 and by WRKY6 in senescent leaves. Also induced 30 minutes after flagellin treatment.

UniProt features for SIRK_ARATH » Senescence-induced receptor-like serine/threonine-protein kinase
SIGNAL 1 24 Potential.
CHAIN 25 876 Senescence-induced receptor-like serine/threonine-protein kinase.
REPEAT 415 438 LRR 1.
REPEAT 439 462 LRR 2.
REPEAT 463 483 LRR 3.
DOMAIN 574 847 Protein kinase.
ACT_SITE 697 697 Proton acceptor (By similarity).
Amino Acid Sequence for SIRK_ARATH » Senescence-induced receptor-like serine/threonine-protein kinase
MAMLKSLSSI LFTSFALLFF LVHAQDQSGF ISIDCGIPDD SSYNDETTGI KYVSDSAFVD SGTTKRIAAQ FQSSGFDRHL LNVRSFPQSK RSCYDVPTPR GKGFKYLIRT RFMYGNYDDL GRVPEFDLYL GVNFWDSVKL DDATTILNKE IITIPLLDNV QVCVVDKNAG TPFLSVLEIR LLLNTTYETP YDALTLLRRL DYSKTGKLPS RYKDDIYDRI WTPRIVSSEY KILNTSLTVD QFLNNGYQPA STVMSTAETA RNESLYLTLS FRPPDPNAKF YVYMHFAEIE VLKSNQTREF SIWLNEDVIS PSFKLRYLLT DTFVTPDPVS GITINFSLLQ PPGEFVLPPI INALEVYQVN EFLQIPTHPQ DVDAMRKIKA TYRVKKNWQG DPCVPVDYSW EGIDCIQSDN TTNPRVVSLN ISFSELRGQI DPAFSNLTSI RKLDLSGNTL TGEIPAFLAN LPNLTELNVE GNKLTGIVPQ RLHERSKNGS LSLRFGRNPD LCLSDSCSNT KKKNKNGYII PLVVVGIIVV LLTALALFRR FKKKQQRGTL GERNGPLKTA KRYFKYSEVV NITNNFERVI GKGGFGKVYH GVINGEQVAV KVLSEESAQG YKEFRAEVDL LMRVHHTNLT SLVGYCNEIN HMVLIYEYMA NENLGDYLAG KRSFILSWEE RLKISLDAAQ GLEYLHNGCK PPIVHRDVKP TNILLNEKLQ AKMADFGLSR SFSVEGSGQI STVVAGSIGY LDPEYYSTRQ MNEKSDVYSL GVVLLEVITG QPAIASSKTE KVHISDHVRS ILANGDIRGI VDQRLRERYD VGSAWKMSEI ALACTEHTSA QRPTMSQVVM ELKQIVYGIV TDQENYDDST KMLTVNLDTE MVPRAR