SIRB2_HUMAN » Signal-regulatory protein beta-2

SIRB2_HUMAN » Signal-regulatory protein beta-2
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Topology in Plasma membrane
Topologyextracellular side
cytoplasmic side
SIRB2_HUMAN » Signal-regulatory protein beta-2 » SIRP-beta-2; Protein tyrosine phosphatase non-receptor type substrate 1-like 3;Protein tyrosine phosphatase non-receptor type substrate protein;
Hydrophobic Thickness 34.8 ± 4.6 Å
Tilt Angle 32 ± 3°
ΔGtransfer -27.7 kcal/mol
ΔGfold -19.2 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 285-313 (285-317)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 43-150, PDBID: 2D9C, Subunit A, Seq Identity:37%, Immunoglobulin V-set domain

AA: 162-264, PDBID: 2YZ1, Subunit B, Seq Identity:40%, Immunoglobulin V-set domain

UniProt features for SIRB2_HUMAN » Signal-regulatory protein beta-2
SIGNAL 1 32 Potential.
CHAIN 33 342 Signal-regulatory protein beta-2.
DOMAIN 33 143 Ig-like V-type 1.
DOMAIN 157 258 Ig-like V-type 2.
DISULFID 60 127 By similarity.
DISULFID 180 242 By similarity.
Amino Acid Sequence for SIRB2_HUMAN » Signal-regulatory protein beta-2
MCSTMSAPTC LAHLPPCFLL LALVLVPSDA SGQSSRNDWQ VLQPEGPMLV AEGETLLLRC MVVGSCTDGM IKWVKVSTQD QQEIYNFKRG SFPGVMPMIQ RTSEPLNCDY SIYIHNVTRE HTGTYHCVRF DGLSEHSEMK SDEGTSVLVK GAGDPEPDLW IIQPQELVLG TTGDTVFLNC TVLGDGPPGP IRWFQGAGLS REAIYNFGGI SHPKETAVQA SNNDFSILLQ NVSSEDAGTY YCVKFQRKPN RQYLSGQGTS LKVKAKSTSS KEAEFTSEPA TEMSPTGLLV VFAPVVLGLK AITLAALLLA LATSRRSPGQ EDVKTTGPAG AMNTLAWSKG QE