SHSA3_HUMAN » Protein shisa-3 homolog

SHSA3_HUMAN » Protein shisa-3 homolog
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Topology in Endoplasmic reticulum membrane
Topologylumenal side
cytoplasmic side
SHSA3_HUMAN » Protein shisa-3 homolog »
Hydrophobic Thickness 35.2 ± 1.8 Å
Tilt Angle 1 ± 0°
ΔGtransfer -48.2 kcal/mol
ΔGfold -17.1 kcal/mol
Links UniProtKB, Pfam, Interpro, iHOP, STRING, HGNC
Topology Out
TM Segments 96-122 (96-125)
Pathways none
PDB none
OPM none
Complexes none
Interactions none
Domains

AA: 25-207, Wnt and FGF inhibitory regulator

UniProt annotation for SHSA3_HUMAN » Protein shisa-3 homolog
FUNCTION: Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling.
UniProt features for SHSA3_HUMAN » Protein shisa-3 homolog
SIGNAL 1 21 Potential.
CHAIN 22 238 Protein shisa-3 homolog.
Amino Acid Sequence for SHSA3_HUMAN » Protein shisa-3 homolog
MRALLALCLL LGWLRWGPAG AQQSGEYCHG WVDVQGNYHE GFQCPEDFDT LDATICCGSC ALRYCCAAAD ARLEQGGCTN DRRELEHPGI TAQPVYVPFL IVGSIFIAFI ILGSVVAIYC CTCLRPKEPS QQPIRFSLRS YQTETLPMIL TSTSPRAPSR QSSTATSSSS TGGSIRRFSF ARAEPGCLVP SPPPPYTTSH SIHLAQPSGF LVSPQYFAYP LQQEPPLPGK SCPDFSSS